Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling

Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling

The molecular mechanisms regulating adult neural stem/progenitor cell differentiation following damage of the central nervous system are unclear. Here, the authors show that fibrinogen is a regulator of the adult neural stem/progenitor cell switch from neurogenesis to astrogenesis in a model of stro...

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Main Authors: Lauriane Pous, Sachin S. Deshpande, Suvra Nath, Szilvia Mezey, Subash C. Malik, Sebastian Schildge, Christian Bohrer, Könül Topp, Dietmar Pfeifer, Francisco Fernández-Klett, Soroush Doostkam, Dennis K. Galanakis, Verdon Taylor, Katerina Akassoglou, Christian Schachtrup
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Science
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Online Access:https://doaj.org/article/f3d973f0777646bfaf11ff6400d0b81e
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