Chondromyxoid Fibroma-Like Osteosarcoma in a 13 Years Old Girl: A Report of a New Case

Osteosarcoma (OS) is the most common primary non hematopoietic malignant tumor of bone with a strict histologic definition: the presence of unequivocal osteoid produced by neoplastic cells. Rare variants displaying low-grade histological features have been described; among which chondromyxoid fibrom...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Sabrine Derqaoui, Oussama Marbouh, Tarik Madhi, Lamalmi Najat, Lamia Rouas
Formato:	article
Lenguaje:	EN
Publicado:	SAGE Publishing 2021
Materias:	Pathology RB1-214
Acceso en línea:	https://doaj.org/article/f3ecd17ab6774d16899dce8e0c770d15
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f3ecd17ab6774d16899dce8e0c770d15
record_format	dspace
spelling	oai:doaj.org-article:f3ecd17ab6774d16899dce8e0c770d152021-11-18T22:33:19ZChondromyxoid Fibroma-Like Osteosarcoma in a 13 Years Old Girl: A Report of a New Case2632-010X10.1177/2632010X211057555https://doaj.org/article/f3ecd17ab6774d16899dce8e0c770d152021-11-01T00:00:00Zhttps://doi.org/10.1177/2632010X211057555https://doaj.org/toc/2632-010XOsteosarcoma (OS) is the most common primary non hematopoietic malignant tumor of bone with a strict histologic definition: the presence of unequivocal osteoid produced by neoplastic cells. Rare variants displaying low-grade histological features have been described; among which chondromyxoid fibroma-like (CMF-OS) is the rarest. However, despite its bland morphology; CMF-like OS has an aggressive clinical behavior and a poor prognosis. To the best of our knowledge, only 3 cases of CMF-OS have been previously reported in children. Because of its atypicality and scarcity; misdiagnosis is more likely to occur. Herein we describe a new case of CMF-OS in a 13 years old girl with fatal outcome. Diagnosis was based on focal malignant bone formation and correlation with imaging studies. The aim of the present case presentation is to raise awareness of this rare entity and to highlight the challenging diagnosisSabrine DerqaouiOussama MarbouhTarik MadhiLamalmi NajatLamia RouasSAGE PublishingarticlePathologyRB1-214ENClinical Pathology, Vol 14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Pathology RB1-214
spellingShingle	Pathology RB1-214 Sabrine Derqaoui Oussama Marbouh Tarik Madhi Lamalmi Najat Lamia Rouas Chondromyxoid Fibroma-Like Osteosarcoma in a 13 Years Old Girl: A Report of a New Case
description	Osteosarcoma (OS) is the most common primary non hematopoietic malignant tumor of bone with a strict histologic definition: the presence of unequivocal osteoid produced by neoplastic cells. Rare variants displaying low-grade histological features have been described; among which chondromyxoid fibroma-like (CMF-OS) is the rarest. However, despite its bland morphology; CMF-like OS has an aggressive clinical behavior and a poor prognosis. To the best of our knowledge, only 3 cases of CMF-OS have been previously reported in children. Because of its atypicality and scarcity; misdiagnosis is more likely to occur. Herein we describe a new case of CMF-OS in a 13 years old girl with fatal outcome. Diagnosis was based on focal malignant bone formation and correlation with imaging studies. The aim of the present case presentation is to raise awareness of this rare entity and to highlight the challenging diagnosis
format	article
author	Sabrine Derqaoui Oussama Marbouh Tarik Madhi Lamalmi Najat Lamia Rouas
author_facet	Sabrine Derqaoui Oussama Marbouh Tarik Madhi Lamalmi Najat Lamia Rouas
author_sort	Sabrine Derqaoui
title	Chondromyxoid Fibroma-Like Osteosarcoma in a 13 Years Old Girl: A Report of a New Case
title_short	Chondromyxoid Fibroma-Like Osteosarcoma in a 13 Years Old Girl: A Report of a New Case
title_full	Chondromyxoid Fibroma-Like Osteosarcoma in a 13 Years Old Girl: A Report of a New Case
title_fullStr	Chondromyxoid Fibroma-Like Osteosarcoma in a 13 Years Old Girl: A Report of a New Case
title_full_unstemmed	Chondromyxoid Fibroma-Like Osteosarcoma in a 13 Years Old Girl: A Report of a New Case
title_sort	chondromyxoid fibroma-like osteosarcoma in a 13 years old girl: a report of a new case
publisher	SAGE Publishing
publishDate	2021
url	https://doaj.org/article/f3ecd17ab6774d16899dce8e0c770d15
work_keys_str_mv	AT sabrinederqaoui chondromyxoidfibromalikeosteosarcomaina13yearsoldgirlareportofanewcase AT oussamamarbouh chondromyxoidfibromalikeosteosarcomaina13yearsoldgirlareportofanewcase AT tarikmadhi chondromyxoidfibromalikeosteosarcomaina13yearsoldgirlareportofanewcase AT lamalminajat chondromyxoidfibromalikeosteosarcomaina13yearsoldgirlareportofanewcase AT lamiarouas chondromyxoidfibromalikeosteosarcomaina13yearsoldgirlareportofanewcase
_version_	1718420704507985920

Chondromyxoid Fibroma-Like Osteosarcoma in a 13 Years Old Girl: A Report of a New Case

Ejemplares similares