Surface protein imputation from single cell transcriptomes by deep neural networks

Cell-surface proteins serve as phenotypic cell markers and in many cases are more indicative of cellular function than the transcriptome. Here, the authors introduce a transfer learning framework to impute surface protein abundances from scRNA-seq data.

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Detalles Bibliográficos
Autores principales: Zilu Zhou, Chengzhong Ye, Jingshu Wang, Nancy R. Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/f3f0dd0683dd476f946e529ea4212892
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