Analyzing effects of sickle cell disease on morphometric and cranial growth in Indian population

Background: Sickle cell disease is the most pervasive autosomal recessive hereditary blood diseases and is characterized by the presence of sickle hemoglobin (HbS), which in turn gives rise to pathophysiological consequences. This HbS reduces the agility of erythrocytes plummeting their ability to p...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Kumari Menka, Kumar Anand, Mrigank Shekhar Jha, Abhinav Goel, Saba Nasreen, Devendra H Palve
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	class ii malocclusion craniofacial features mandibular retrognathism sickle cell anemia sickle cell disease Pharmacy and materia medica RS1-441 Analytical chemistry QD71-142
Acceso en línea:	https://doaj.org/article/f40bae88c4f245f8a03dc6bff878e7b8
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f40bae88c4f245f8a03dc6bff878e7b8
record_format	dspace
spelling	oai:doaj.org-article:f40bae88c4f245f8a03dc6bff878e7b82021-11-19T12:15:53ZAnalyzing effects of sickle cell disease on morphometric and cranial growth in Indian population0975-740610.4103/jpbs.jpbs_227_21https://doaj.org/article/f40bae88c4f245f8a03dc6bff878e7b82021-01-01T00:00:00Zhttp://www.jpbsonline.org/article.asp?issn=0975-7406;year=2021;volume=13;issue=6;spage=1402;epage=1405;aulast=Menkahttps://doaj.org/toc/0975-7406Background: Sickle cell disease is the most pervasive autosomal recessive hereditary blood diseases and is characterized by the presence of sickle hemoglobin (HbS), which in turn gives rise to pathophysiological consequences. This HbS reduces the agility of erythrocytes plummeting their ability to pass through small vascular channels, which in turn results in increased blood viscosity and congestion of vascular beds, causing ischemia, local infarction, and hemolysis. Objectives: The current study was conducted to carry out the morphometric analysis in patients with sickle cell disease. Materials and Methods: This study was conducted on 75 subjects detected with sickle cell disease aged between 8 and 16.5 years. The study involved 38 males and 37 females. All the subjects were subjected to lateral cephalogram for the calculation of various angular and linear dimensions of the craniofacial structures. The linear measurements made were nasion-menton height, anterior nasal spine (ANS)-menton height, and nasion-ANS height, whereas the angular measurements made were Frankfurt mandibular plane angle, Frankfort mandibular incisor angle, and incisor mandibular plane angle. Results: Major chunk of the subjects had retruded mandible and vertical growth pattern. Few subjects exhibited with maxillary protrusion. Conclusion: It is concluded that early diagnosis and management of dental malocclusion in patients with sickle cell disease plays a pivotal role in an attempt to endow with a better quality of life to these individuals.Kumari MenkaKumar AnandMrigank Shekhar JhaAbhinav GoelSaba NasreenDevendra H PalveWolters Kluwer Medknow Publicationsarticleclass ii malocclusioncraniofacial featuresmandibular retrognathismsickle cell anemiasickle cell diseasePharmacy and materia medicaRS1-441Analytical chemistryQD71-142ENJournal of Pharmacy and Bioallied Sciences, Vol 13, Iss 6, Pp 1402-1405 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	class ii malocclusion craniofacial features mandibular retrognathism sickle cell anemia sickle cell disease Pharmacy and materia medica RS1-441 Analytical chemistry QD71-142
spellingShingle	class ii malocclusion craniofacial features mandibular retrognathism sickle cell anemia sickle cell disease Pharmacy and materia medica RS1-441 Analytical chemistry QD71-142 Kumari Menka Kumar Anand Mrigank Shekhar Jha Abhinav Goel Saba Nasreen Devendra H Palve Analyzing effects of sickle cell disease on morphometric and cranial growth in Indian population
description	Background: Sickle cell disease is the most pervasive autosomal recessive hereditary blood diseases and is characterized by the presence of sickle hemoglobin (HbS), which in turn gives rise to pathophysiological consequences. This HbS reduces the agility of erythrocytes plummeting their ability to pass through small vascular channels, which in turn results in increased blood viscosity and congestion of vascular beds, causing ischemia, local infarction, and hemolysis. Objectives: The current study was conducted to carry out the morphometric analysis in patients with sickle cell disease. Materials and Methods: This study was conducted on 75 subjects detected with sickle cell disease aged between 8 and 16.5 years. The study involved 38 males and 37 females. All the subjects were subjected to lateral cephalogram for the calculation of various angular and linear dimensions of the craniofacial structures. The linear measurements made were nasion-menton height, anterior nasal spine (ANS)-menton height, and nasion-ANS height, whereas the angular measurements made were Frankfurt mandibular plane angle, Frankfort mandibular incisor angle, and incisor mandibular plane angle. Results: Major chunk of the subjects had retruded mandible and vertical growth pattern. Few subjects exhibited with maxillary protrusion. Conclusion: It is concluded that early diagnosis and management of dental malocclusion in patients with sickle cell disease plays a pivotal role in an attempt to endow with a better quality of life to these individuals.
format	article
author	Kumari Menka Kumar Anand Mrigank Shekhar Jha Abhinav Goel Saba Nasreen Devendra H Palve
author_facet	Kumari Menka Kumar Anand Mrigank Shekhar Jha Abhinav Goel Saba Nasreen Devendra H Palve
author_sort	Kumari Menka
title	Analyzing effects of sickle cell disease on morphometric and cranial growth in Indian population
title_short	Analyzing effects of sickle cell disease on morphometric and cranial growth in Indian population
title_full	Analyzing effects of sickle cell disease on morphometric and cranial growth in Indian population
title_fullStr	Analyzing effects of sickle cell disease on morphometric and cranial growth in Indian population
title_full_unstemmed	Analyzing effects of sickle cell disease on morphometric and cranial growth in Indian population
title_sort	analyzing effects of sickle cell disease on morphometric and cranial growth in indian population
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/f40bae88c4f245f8a03dc6bff878e7b8
work_keys_str_mv	AT kumarimenka analyzingeffectsofsicklecelldiseaseonmorphometricandcranialgrowthinindianpopulation AT kumaranand analyzingeffectsofsicklecelldiseaseonmorphometricandcranialgrowthinindianpopulation AT mrigankshekharjha analyzingeffectsofsicklecelldiseaseonmorphometricandcranialgrowthinindianpopulation AT abhinavgoel analyzingeffectsofsicklecelldiseaseonmorphometricandcranialgrowthinindianpopulation AT sabanasreen analyzingeffectsofsicklecelldiseaseonmorphometricandcranialgrowthinindianpopulation AT devendrahpalve analyzingeffectsofsicklecelldiseaseonmorphometricandcranialgrowthinindianpopulation
_version_	1718420168875442176

Analyzing effects of sickle cell disease on morphometric and cranial growth in Indian population

Ejemplares similares