A novel 3D-printed head phantom with anatomically realistic geometry and continuously varying skull resistivity distribution for electrical impedance tomography

Abstract Phantom experiments are an important step for testing during the development of new hardware or imaging algorithms for head electrical impedance tomography (EIT) studies. However, due to the sophisticated anatomical geometry and complex resistivity distribution of the human head, constructi...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Jie Zhang, Bin Yang, Haoting Li, Feng Fu, Xuetao Shi, Xiuzhen Dong, Meng Dai
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/f419aac6fb2c4ff2ac2693d5f79244a1
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f419aac6fb2c4ff2ac2693d5f79244a1
record_format	dspace
spelling	oai:doaj.org-article:f419aac6fb2c4ff2ac2693d5f79244a12021-12-02T11:52:23ZA novel 3D-printed head phantom with anatomically realistic geometry and continuously varying skull resistivity distribution for electrical impedance tomography10.1038/s41598-017-05006-82045-2322https://doaj.org/article/f419aac6fb2c4ff2ac2693d5f79244a12017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-05006-8https://doaj.org/toc/2045-2322Abstract Phantom experiments are an important step for testing during the development of new hardware or imaging algorithms for head electrical impedance tomography (EIT) studies. However, due to the sophisticated anatomical geometry and complex resistivity distribution of the human head, constructing an accurate phantom for EIT research remains challenging, especially for skull modelling. In this paper, we designed and fabricated a novel head phantom with anatomically realistic geometry and continuously varying skull resistivity distribution based on 3D printing techniques. The skull model was constructed by simultaneously printing the distinct layers inside the skull with resistivity-controllable printing materials. The entire phantom was composed of saline skin, a 3D-printed skull, saline cerebrospinal fluid (CSF) and 3D-printed brain parenchyma. The validation results demonstrated that the resistivity of the phantom was in good agreement with that of human tissue and was stable over time, and the new phantom performed well in EIT imaging. This paper provides a standardized, efficient and reproducible method for the construction of a head phantom for EIT that could be easily adapted to other conditions for manufacturing head phantoms for brain function research, such as transcranial direct current stimulation (TDCS) and electroencephalography (EEG).Jie ZhangBin YangHaoting LiFeng FuXuetao ShiXiuzhen DongMeng DaiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Jie Zhang Bin Yang Haoting Li Feng Fu Xuetao Shi Xiuzhen Dong Meng Dai A novel 3D-printed head phantom with anatomically realistic geometry and continuously varying skull resistivity distribution for electrical impedance tomography
description	Abstract Phantom experiments are an important step for testing during the development of new hardware or imaging algorithms for head electrical impedance tomography (EIT) studies. However, due to the sophisticated anatomical geometry and complex resistivity distribution of the human head, constructing an accurate phantom for EIT research remains challenging, especially for skull modelling. In this paper, we designed and fabricated a novel head phantom with anatomically realistic geometry and continuously varying skull resistivity distribution based on 3D printing techniques. The skull model was constructed by simultaneously printing the distinct layers inside the skull with resistivity-controllable printing materials. The entire phantom was composed of saline skin, a 3D-printed skull, saline cerebrospinal fluid (CSF) and 3D-printed brain parenchyma. The validation results demonstrated that the resistivity of the phantom was in good agreement with that of human tissue and was stable over time, and the new phantom performed well in EIT imaging. This paper provides a standardized, efficient and reproducible method for the construction of a head phantom for EIT that could be easily adapted to other conditions for manufacturing head phantoms for brain function research, such as transcranial direct current stimulation (TDCS) and electroencephalography (EEG).
format	article
author	Jie Zhang Bin Yang Haoting Li Feng Fu Xuetao Shi Xiuzhen Dong Meng Dai
author_facet	Jie Zhang Bin Yang Haoting Li Feng Fu Xuetao Shi Xiuzhen Dong Meng Dai
author_sort	Jie Zhang
title	A novel 3D-printed head phantom with anatomically realistic geometry and continuously varying skull resistivity distribution for electrical impedance tomography
title_short	A novel 3D-printed head phantom with anatomically realistic geometry and continuously varying skull resistivity distribution for electrical impedance tomography
title_full	A novel 3D-printed head phantom with anatomically realistic geometry and continuously varying skull resistivity distribution for electrical impedance tomography
title_fullStr	A novel 3D-printed head phantom with anatomically realistic geometry and continuously varying skull resistivity distribution for electrical impedance tomography
title_full_unstemmed	A novel 3D-printed head phantom with anatomically realistic geometry and continuously varying skull resistivity distribution for electrical impedance tomography
title_sort	novel 3d-printed head phantom with anatomically realistic geometry and continuously varying skull resistivity distribution for electrical impedance tomography
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/f419aac6fb2c4ff2ac2693d5f79244a1
work_keys_str_mv	AT jiezhang anovel3dprintedheadphantomwithanatomicallyrealisticgeometryandcontinuouslyvaryingskullresistivitydistributionforelectricalimpedancetomography AT binyang anovel3dprintedheadphantomwithanatomicallyrealisticgeometryandcontinuouslyvaryingskullresistivitydistributionforelectricalimpedancetomography AT haotingli anovel3dprintedheadphantomwithanatomicallyrealisticgeometryandcontinuouslyvaryingskullresistivitydistributionforelectricalimpedancetomography AT fengfu anovel3dprintedheadphantomwithanatomicallyrealisticgeometryandcontinuouslyvaryingskullresistivitydistributionforelectricalimpedancetomography AT xuetaoshi anovel3dprintedheadphantomwithanatomicallyrealisticgeometryandcontinuouslyvaryingskullresistivitydistributionforelectricalimpedancetomography AT xiuzhendong anovel3dprintedheadphantomwithanatomicallyrealisticgeometryandcontinuouslyvaryingskullresistivitydistributionforelectricalimpedancetomography AT mengdai anovel3dprintedheadphantomwithanatomicallyrealisticgeometryandcontinuouslyvaryingskullresistivitydistributionforelectricalimpedancetomography AT jiezhang novel3dprintedheadphantomwithanatomicallyrealisticgeometryandcontinuouslyvaryingskullresistivitydistributionforelectricalimpedancetomography AT binyang novel3dprintedheadphantomwithanatomicallyrealisticgeometryandcontinuouslyvaryingskullresistivitydistributionforelectricalimpedancetomography AT haotingli novel3dprintedheadphantomwithanatomicallyrealisticgeometryandcontinuouslyvaryingskullresistivitydistributionforelectricalimpedancetomography AT fengfu novel3dprintedheadphantomwithanatomicallyrealisticgeometryandcontinuouslyvaryingskullresistivitydistributionforelectricalimpedancetomography AT xuetaoshi novel3dprintedheadphantomwithanatomicallyrealisticgeometryandcontinuouslyvaryingskullresistivitydistributionforelectricalimpedancetomography AT xiuzhendong novel3dprintedheadphantomwithanatomicallyrealisticgeometryandcontinuouslyvaryingskullresistivitydistributionforelectricalimpedancetomography AT mengdai novel3dprintedheadphantomwithanatomicallyrealisticgeometryandcontinuouslyvaryingskullresistivitydistributionforelectricalimpedancetomography
_version_	1718395082020749312

A novel 3D-printed head phantom with anatomically realistic geometry and continuously varying skull resistivity distribution for electrical impedance tomography

Ejemplares similares