COMPARATIVE EFFICACY OF ORAL FLUCONAZOLE AND ORAL ITRACONAZOLE IN PITYRIASIS VERSICOLOR

Objective: To compare the efficacy of oral fluconazole and oral itraconazole in the treatment of Pityriasis versicolor. Study Design: Comparative prospective study. Methodology: Total 72 patients of both genders with Pityriasis versicolor were included. Patients were randomly allocated into t...

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Autores principales:	Muhammad Rizwan, Naeem Raza, Ayesha Anwar, Ayesha Khokhar
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2021
Materias:	efficacy fluconazole itraconazole pityriasis versicolor Medicine R Medicine (General) R5-920
Acceso en línea:	https://doi.org/10.51253/pafmj.v71iSuppl-1.4555 https://doaj.org/article/f41e9f5272644d6eaea13345aed42821
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spelling	oai:doaj.org-article:f41e9f5272644d6eaea13345aed428212021-12-02T17:18:52ZCOMPARATIVE EFFICACY OF ORAL FLUCONAZOLE AND ORAL ITRACONAZOLE IN PITYRIASIS VERSICOLORhttps://doi.org/10.51253/pafmj.v71iSuppl-1.45550030-96482411-8842https://doaj.org/article/f41e9f5272644d6eaea13345aed428212021-01-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/4555https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To compare the efficacy of oral fluconazole and oral itraconazole in the treatment of Pityriasis versicolor. Study Design: Comparative prospective study. Methodology: Total 72 patients of both genders with Pityriasis versicolor were included. Patients were randomly allocated into two treatment groups with 36 patients in each group: group A and group B by lottery method. Patients in group A received Cap Fluconazole 150 mg bi- weekly for two consecutive weeks while those in group B received two doses of 400 mg of itraconazole once weekly for two weeks. Patients were asked to follow-up after 4 weeks skin scrapings for microscopy using 10% KOH mount was done at follow-up. Efficacy was assessed in terms of negative fungal hyphae on microscopy. Results: In this study, age ranged from 18 to 40 years with mean age of 33.52 ± 4.12 years in group A, whereas 35.055 ± 4.18 years in group B. Mean duration of disease was 4.66 ± 1.51 months in group A and 5.27 ± 1.70 months in group B. Efficacy was seen in 77.8% of group A patients as compared to 50% in group B patients (p=0.014). Conclusion: Oral Fluconazole two doses of 150 mg/week (total 300mg/week) for two consecutive weeks was found more effective than oral itraconazole.Muhammad RizwanNaeem RazaAyesha AnwarAyesha KhokharArmy Medical College Rawalpindiarticleefficacyfluconazoleitraconazolepityriasis versicolorMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 71, Iss SUPPL-1, Pp 273-276 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	efficacy fluconazole itraconazole pityriasis versicolor Medicine R Medicine (General) R5-920
spellingShingle	efficacy fluconazole itraconazole pityriasis versicolor Medicine R Medicine (General) R5-920 Muhammad Rizwan Naeem Raza Ayesha Anwar Ayesha Khokhar COMPARATIVE EFFICACY OF ORAL FLUCONAZOLE AND ORAL ITRACONAZOLE IN PITYRIASIS VERSICOLOR
description	Objective: To compare the efficacy of oral fluconazole and oral itraconazole in the treatment of Pityriasis versicolor. Study Design: Comparative prospective study. Methodology: Total 72 patients of both genders with Pityriasis versicolor were included. Patients were randomly allocated into two treatment groups with 36 patients in each group: group A and group B by lottery method. Patients in group A received Cap Fluconazole 150 mg bi- weekly for two consecutive weeks while those in group B received two doses of 400 mg of itraconazole once weekly for two weeks. Patients were asked to follow-up after 4 weeks skin scrapings for microscopy using 10% KOH mount was done at follow-up. Efficacy was assessed in terms of negative fungal hyphae on microscopy. Results: In this study, age ranged from 18 to 40 years with mean age of 33.52 ± 4.12 years in group A, whereas 35.055 ± 4.18 years in group B. Mean duration of disease was 4.66 ± 1.51 months in group A and 5.27 ± 1.70 months in group B. Efficacy was seen in 77.8% of group A patients as compared to 50% in group B patients (p=0.014). Conclusion: Oral Fluconazole two doses of 150 mg/week (total 300mg/week) for two consecutive weeks was found more effective than oral itraconazole.
format	article
author	Muhammad Rizwan Naeem Raza Ayesha Anwar Ayesha Khokhar
author_facet	Muhammad Rizwan Naeem Raza Ayesha Anwar Ayesha Khokhar
author_sort	Muhammad Rizwan
title	COMPARATIVE EFFICACY OF ORAL FLUCONAZOLE AND ORAL ITRACONAZOLE IN PITYRIASIS VERSICOLOR
title_short	COMPARATIVE EFFICACY OF ORAL FLUCONAZOLE AND ORAL ITRACONAZOLE IN PITYRIASIS VERSICOLOR
title_full	COMPARATIVE EFFICACY OF ORAL FLUCONAZOLE AND ORAL ITRACONAZOLE IN PITYRIASIS VERSICOLOR
title_fullStr	COMPARATIVE EFFICACY OF ORAL FLUCONAZOLE AND ORAL ITRACONAZOLE IN PITYRIASIS VERSICOLOR
title_full_unstemmed	COMPARATIVE EFFICACY OF ORAL FLUCONAZOLE AND ORAL ITRACONAZOLE IN PITYRIASIS VERSICOLOR
title_sort	comparative efficacy of oral fluconazole and oral itraconazole in pityriasis versicolor
publisher	Army Medical College Rawalpindi
publishDate	2021
url	https://doi.org/10.51253/pafmj.v71iSuppl-1.4555 https://doaj.org/article/f41e9f5272644d6eaea13345aed42821
work_keys_str_mv	AT muhammadrizwan comparativeefficacyoforalfluconazoleandoralitraconazoleinpityriasisversicolor AT naeemraza comparativeefficacyoforalfluconazoleandoralitraconazoleinpityriasisversicolor AT ayeshaanwar comparativeefficacyoforalfluconazoleandoralitraconazoleinpityriasisversicolor AT ayeshakhokhar comparativeefficacyoforalfluconazoleandoralitraconazoleinpityriasisversicolor
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COMPARATIVE EFFICACY OF ORAL FLUCONAZOLE AND ORAL ITRACONAZOLE IN PITYRIASIS VERSICOLOR

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