Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors

Highly sensitive urea sensors can now be made with direct infrared laser writing on cheap Kapton sheets A collaborative international team led by Dr. Swati Sharma from Karlsruhe Institute of Technology, Germany demonstrates the first catheter-compatible, pH-based enzymatic urea sensor. The authors d...

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Autores principales: Emil R. Mamleyev, Stefan Heissler, Alexei Nefedov, Peter G. Weidler, Nurdiana Nordin, Vladislav V. Kudryashov, Kerstin Länge, Neil MacKinnon, Swati Sharma
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Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/f41f532e51e849fe90a029d41465439c
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spelling oai:doaj.org-article:f41f532e51e849fe90a029d41465439c2021-12-02T18:17:29ZLaser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors10.1038/s41528-018-0047-82397-4621https://doaj.org/article/f41f532e51e849fe90a029d41465439c2019-01-01T00:00:00Zhttps://doi.org/10.1038/s41528-018-0047-8https://doaj.org/toc/2397-4621Highly sensitive urea sensors can now be made with direct infrared laser writing on cheap Kapton sheets A collaborative international team led by Dr. Swati Sharma from Karlsruhe Institute of Technology, Germany demonstrates the first catheter-compatible, pH-based enzymatic urea sensor. The authors directly convert commercially available Kapton films into carbon using IR laser, and optimize the process for obtaining a high surface area material with hydrophilic functional groups for biosensor fabrication. These inexpensive flexible sensors are fabricated by enzyme absorption on to the carbon films, with or without an electrodeposited intermediate chitosan layer. They can be rolled-up to fit inside a catheter tube, and feature detection limit down to 10−4 M urea concentration that is 100 times lower than that in the blood serum of a healthy human. These sensors show promising applications as they are inexpensive, flexible, readily usable for in-vivo urea determination and easily extendable to multi- functional circuits.Emil R. MamleyevStefan HeisslerAlexei NefedovPeter G. WeidlerNurdiana NordinVladislav V. KudryashovKerstin LängeNeil MacKinnonSwati SharmaNature PortfolioarticleElectronicsTK7800-8360Materials of engineering and construction. Mechanics of materialsTA401-492ENnpj Flexible Electronics, Vol 3, Iss 1, Pp 1-11 (2019)
institution DOAJ
collection DOAJ
language EN
topic Electronics
TK7800-8360
Materials of engineering and construction. Mechanics of materials
TA401-492
spellingShingle Electronics
TK7800-8360
Materials of engineering and construction. Mechanics of materials
TA401-492
Emil R. Mamleyev
Stefan Heissler
Alexei Nefedov
Peter G. Weidler
Nurdiana Nordin
Vladislav V. Kudryashov
Kerstin Länge
Neil MacKinnon
Swati Sharma
Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors
description Highly sensitive urea sensors can now be made with direct infrared laser writing on cheap Kapton sheets A collaborative international team led by Dr. Swati Sharma from Karlsruhe Institute of Technology, Germany demonstrates the first catheter-compatible, pH-based enzymatic urea sensor. The authors directly convert commercially available Kapton films into carbon using IR laser, and optimize the process for obtaining a high surface area material with hydrophilic functional groups for biosensor fabrication. These inexpensive flexible sensors are fabricated by enzyme absorption on to the carbon films, with or without an electrodeposited intermediate chitosan layer. They can be rolled-up to fit inside a catheter tube, and feature detection limit down to 10−4 M urea concentration that is 100 times lower than that in the blood serum of a healthy human. These sensors show promising applications as they are inexpensive, flexible, readily usable for in-vivo urea determination and easily extendable to multi- functional circuits.
format article
author Emil R. Mamleyev
Stefan Heissler
Alexei Nefedov
Peter G. Weidler
Nurdiana Nordin
Vladislav V. Kudryashov
Kerstin Länge
Neil MacKinnon
Swati Sharma
author_facet Emil R. Mamleyev
Stefan Heissler
Alexei Nefedov
Peter G. Weidler
Nurdiana Nordin
Vladislav V. Kudryashov
Kerstin Länge
Neil MacKinnon
Swati Sharma
author_sort Emil R. Mamleyev
title Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors
title_short Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors
title_full Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors
title_fullStr Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors
title_full_unstemmed Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors
title_sort laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/f41f532e51e849fe90a029d41465439c
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