Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors
Highly sensitive urea sensors can now be made with direct infrared laser writing on cheap Kapton sheets A collaborative international team led by Dr. Swati Sharma from Karlsruhe Institute of Technology, Germany demonstrates the first catheter-compatible, pH-based enzymatic urea sensor. The authors d...
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Nature Portfolio
2019
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oai:doaj.org-article:f41f532e51e849fe90a029d41465439c2021-12-02T18:17:29ZLaser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors10.1038/s41528-018-0047-82397-4621https://doaj.org/article/f41f532e51e849fe90a029d41465439c2019-01-01T00:00:00Zhttps://doi.org/10.1038/s41528-018-0047-8https://doaj.org/toc/2397-4621Highly sensitive urea sensors can now be made with direct infrared laser writing on cheap Kapton sheets A collaborative international team led by Dr. Swati Sharma from Karlsruhe Institute of Technology, Germany demonstrates the first catheter-compatible, pH-based enzymatic urea sensor. The authors directly convert commercially available Kapton films into carbon using IR laser, and optimize the process for obtaining a high surface area material with hydrophilic functional groups for biosensor fabrication. These inexpensive flexible sensors are fabricated by enzyme absorption on to the carbon films, with or without an electrodeposited intermediate chitosan layer. They can be rolled-up to fit inside a catheter tube, and feature detection limit down to 10−4 M urea concentration that is 100 times lower than that in the blood serum of a healthy human. These sensors show promising applications as they are inexpensive, flexible, readily usable for in-vivo urea determination and easily extendable to multi- functional circuits.Emil R. MamleyevStefan HeisslerAlexei NefedovPeter G. WeidlerNurdiana NordinVladislav V. KudryashovKerstin LängeNeil MacKinnonSwati SharmaNature PortfolioarticleElectronicsTK7800-8360Materials of engineering and construction. Mechanics of materialsTA401-492ENnpj Flexible Electronics, Vol 3, Iss 1, Pp 1-11 (2019) |
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Electronics TK7800-8360 Materials of engineering and construction. Mechanics of materials TA401-492 |
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Electronics TK7800-8360 Materials of engineering and construction. Mechanics of materials TA401-492 Emil R. Mamleyev Stefan Heissler Alexei Nefedov Peter G. Weidler Nurdiana Nordin Vladislav V. Kudryashov Kerstin Länge Neil MacKinnon Swati Sharma Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors |
description |
Highly sensitive urea sensors can now be made with direct infrared laser writing on cheap Kapton sheets A collaborative international team led by Dr. Swati Sharma from Karlsruhe Institute of Technology, Germany demonstrates the first catheter-compatible, pH-based enzymatic urea sensor. The authors directly convert commercially available Kapton films into carbon using IR laser, and optimize the process for obtaining a high surface area material with hydrophilic functional groups for biosensor fabrication. These inexpensive flexible sensors are fabricated by enzyme absorption on to the carbon films, with or without an electrodeposited intermediate chitosan layer. They can be rolled-up to fit inside a catheter tube, and feature detection limit down to 10−4 M urea concentration that is 100 times lower than that in the blood serum of a healthy human. These sensors show promising applications as they are inexpensive, flexible, readily usable for in-vivo urea determination and easily extendable to multi- functional circuits. |
format |
article |
author |
Emil R. Mamleyev Stefan Heissler Alexei Nefedov Peter G. Weidler Nurdiana Nordin Vladislav V. Kudryashov Kerstin Länge Neil MacKinnon Swati Sharma |
author_facet |
Emil R. Mamleyev Stefan Heissler Alexei Nefedov Peter G. Weidler Nurdiana Nordin Vladislav V. Kudryashov Kerstin Länge Neil MacKinnon Swati Sharma |
author_sort |
Emil R. Mamleyev |
title |
Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors |
title_short |
Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors |
title_full |
Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors |
title_fullStr |
Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors |
title_full_unstemmed |
Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors |
title_sort |
laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/f41f532e51e849fe90a029d41465439c |
work_keys_str_mv |
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1718378309143756800 |