Evaluation of the sublingual route for administration of influenza H5N1 virosomes in combination with the bacterial second messenger c-di-GMP.

Avian influenza A H5N1 is a virus with pandemic potential. Mucosal vaccines are attractive as they have the potential to block viruses at the site of entry, thereby preventing both disease and further transmission. The intranasal route is safe for the administration of seasonal live-attenuated influ...

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Autores principales: Gabriel Kristian Pedersen, Thomas Ebensen, Ingrid Hjetland Gjeraker, Signe Svindland, Geir Bredholt, Carlos Alberto Guzmán, Rebecca Jane Cox
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/f41fe55c0a8b464e963489b406c956ad
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