GFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors

GFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors

Helness et al. show that GFI1/CHD4 complexes critically regulate chromatin accessibility and histone modifications to regulate target genes affecting diverse cellular processes in neutrophils. Their results provide further insight into the molecular network operated by GFI1 for neutrophil differenti...

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Autores principales: Anne Helness, Jennifer Fraszczak, Charles Joly-Beauparlant, Halil Bagci, Christian Trahan, Kaifee Arman, Peiman Shooshtarizadeh, Riyan Chen, Marina Ayoub, Jean-François Côté, Marlene Oeffinger, Arnaud Droit, Tarik Möröy
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/f4208fa66ce144baa1f83bed6e3a7a19
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spelling oai:doaj.org-article:f4208fa66ce144baa1f83bed6e3a7a192021-12-05T12:08:13ZGFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors10.1038/s42003-021-02889-22399-3642https://doaj.org/article/f4208fa66ce144baa1f83bed6e3a7a192021-12-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02889-2https://doaj.org/toc/2399-3642Helness et al. show that GFI1/CHD4 complexes critically regulate chromatin accessibility and histone modifications to regulate target genes affecting diverse cellular processes in neutrophils. Their results provide further insight into the molecular network operated by GFI1 for neutrophil differentiation programs.Anne HelnessJennifer FraszczakCharles Joly-BeauparlantHalil BagciChristian TrahanKaifee ArmanPeiman ShooshtarizadehRiyan ChenMarina AyoubJean-François CôtéMarlene OeffingerArnaud DroitTarik MöröyNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Anne Helness
Jennifer Fraszczak
Charles Joly-Beauparlant
Halil Bagci
Christian Trahan
Kaifee Arman
Peiman Shooshtarizadeh
Riyan Chen
Marina Ayoub
Jean-François Côté
Marlene Oeffinger
Arnaud Droit
Tarik Möröy
GFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors
description Helness et al. show that GFI1/CHD4 complexes critically regulate chromatin accessibility and histone modifications to regulate target genes affecting diverse cellular processes in neutrophils. Their results provide further insight into the molecular network operated by GFI1 for neutrophil differentiation programs.
format article
author Anne Helness
Jennifer Fraszczak
Charles Joly-Beauparlant
Halil Bagci
Christian Trahan
Kaifee Arman
Peiman Shooshtarizadeh
Riyan Chen
Marina Ayoub
Jean-François Côté
Marlene Oeffinger
Arnaud Droit
Tarik Möröy
author_facet Anne Helness
Jennifer Fraszczak
Charles Joly-Beauparlant
Halil Bagci
Christian Trahan
Kaifee Arman
Peiman Shooshtarizadeh
Riyan Chen
Marina Ayoub
Jean-François Côté
Marlene Oeffinger
Arnaud Droit
Tarik Möröy
author_sort Anne Helness
title GFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors
title_short GFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors
title_full GFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors
title_fullStr GFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors
title_full_unstemmed GFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors
title_sort gfi1 tethers the nurd complex to open and transcriptionally active chromatin in myeloid progenitors
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/f4208fa66ce144baa1f83bed6e3a7a19
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