GFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors
Helness et al. show that GFI1/CHD4 complexes critically regulate chromatin accessibility and histone modifications to regulate target genes affecting diverse cellular processes in neutrophils. Their results provide further insight into the molecular network operated by GFI1 for neutrophil differenti...
Enregistré dans:
Auteurs principaux: | Anne Helness, Jennifer Fraszczak, Charles Joly-Beauparlant, Halil Bagci, Christian Trahan, Kaifee Arman, Peiman Shooshtarizadeh, Riyan Chen, Marina Ayoub, Jean-François Côté, Marlene Oeffinger, Arnaud Droit, Tarik Möröy |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/f4208fa66ce144baa1f83bed6e3a7a19 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes
par: Peiman Shooshtarizadeh, et autres
Publié: (2019) -
NuRD-interacting protein ZFP296 regulates genome-wide NuRD localization and differentiation of mouse embryonic stem cells
par: Susan L. Kloet, et autres
Publié: (2018) -
GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1
par: Charles Vadnais, et autres
Publié: (2018) -
A Casz1–NuRD complex regulates temporal identity transitions in neural progenitors
par: Pierre Mattar, et autres
Publié: (2021) -
PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex
par: Stephanie Link, et autres
Publié: (2018)