TCP1 increases drug resistance in acute myeloid leukemia by suppressing autophagy via activating AKT/mTOR signaling
Abstract T-complex protein 1 (TCP1) is one of the subunits of chaperonin-containing T complex (CCT), which is involved in protein folding, cell proliferation, apoptosis, cell cycle regulation, and drug resistance. Investigations have demonstrated that TCP1 is a factor being responsible for drug resi...
Guardado en:
Autores principales: | Xiaofang Chen, Xianling Chen, Yiping Huang, Jia Lin, Yong Wu, Yuanzhong Chen |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Publishing Group
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/f424132d7cbe4f8fa850eca13c646b18 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Fasting promotes acute hypoxic adaptation by suppressing mTOR-mediated pathways
por: Ruzhou Zhao, et al.
Publicado: (2021) -
OM-MSCs Alleviate the Golgi Apparatus Stress Response following Cerebral Ischemia/Reperfusion Injury via the PEDF-PI3K/Akt/mTOR Signaling Pathway
por: Jialin He, et al.
Publicado: (2021) -
A gene toolbox for monitoring autophagy transcription
por: Matteo Bordi, et al.
Publicado: (2021) -
Cdc25A inhibits autophagy-mediated ferroptosis by upregulating ErbB2 through PKM2 dephosphorylation in cervical cancer cells
por: Chen Wang, et al.
Publicado: (2021) -
TRAIL/DR5 pathway promotes AKT phosphorylation, skeletal muscle differentiation, and glucose uptake
por: Barbara Toffoli, et al.
Publicado: (2021)