FEATURES OF CELLULAR AND HUMORAL IMMUNITY IN ACUTE AND CHRONIC VIRAL HEPATITIS В

We investigated immunological paгameters in patients with acute (AVHB) and chronic hepatitis B. It is established that changing the values of immunological parameters can determine the nature of the infection couse in chronic viral hepatitis B and select at least two types of immune response. The fi...

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Autores principales:	A. G. Borisov, A. A. Savchenko
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2012
Materias:	hepatitis lymphocytes immunoglobulins Science Q
Acceso en línea:	https://doaj.org/article/f42c69fca70a4b6b845a167cc12dddcc
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spelling	oai:doaj.org-article:f42c69fca70a4b6b845a167cc12dddcc2021-11-23T06:14:19ZFEATURES OF CELLULAR AND HUMORAL IMMUNITY IN ACUTE AND CHRONIC VIRAL HEPATITIS В2541-94202587-9596https://doaj.org/article/f42c69fca70a4b6b845a167cc12dddcc2012-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/884https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596We investigated immunological paгameters in patients with acute (AVHB) and chronic hepatitis B. It is established that changing the values of immunological parameters can determine the nature of the infection couse in chronic viral hepatitis B and select at least two types of immune response. The first type (hyperergic) is characterized by high values of immunological indicator, determined by increasing the content of CD3+-lymphocytes with a dysregulation in the subpopulation of T-cells and an increase in humoral immunity. The second (hypoergic) — decrease in the number of T-cells, CD4+- and CD8+-lymphocytes, and various types of immunoglobulins. When AVHB development of acute infection is associated with a reduction in the number of T-lymphocytes, mainly due to the population of CD4+-lymphocytes, increased concentration of immunoglobulins and the CIC, which also indicates the hypoergic type of immune response in acute viral infection.A. G. BorisovA. A. SavchenkoScientific Сentre for Family Health and Human Reproduction ProblemsarticlehepatitislymphocytesimmunoglobulinsScienceQRUActa Biomedica Scientifica, Vol 0, Iss 3(2), Pp 53-57 (2012)
institution	DOAJ
collection	DOAJ
language	RU
topic	hepatitis lymphocytes immunoglobulins Science Q
spellingShingle	hepatitis lymphocytes immunoglobulins Science Q A. G. Borisov A. A. Savchenko FEATURES OF CELLULAR AND HUMORAL IMMUNITY IN ACUTE AND CHRONIC VIRAL HEPATITIS В
description	We investigated immunological paгameters in patients with acute (AVHB) and chronic hepatitis B. It is established that changing the values of immunological parameters can determine the nature of the infection couse in chronic viral hepatitis B and select at least two types of immune response. The first type (hyperergic) is characterized by high values of immunological indicator, determined by increasing the content of CD3+-lymphocytes with a dysregulation in the subpopulation of T-cells and an increase in humoral immunity. The second (hypoergic) — decrease in the number of T-cells, CD4+- and CD8+-lymphocytes, and various types of immunoglobulins. When AVHB development of acute infection is associated with a reduction in the number of T-lymphocytes, mainly due to the population of CD4+-lymphocytes, increased concentration of immunoglobulins and the CIC, which also indicates the hypoergic type of immune response in acute viral infection.
format	article
author	A. G. Borisov A. A. Savchenko
author_facet	A. G. Borisov A. A. Savchenko
author_sort	A. G. Borisov
title	FEATURES OF CELLULAR AND HUMORAL IMMUNITY IN ACUTE AND CHRONIC VIRAL HEPATITIS В
title_short	FEATURES OF CELLULAR AND HUMORAL IMMUNITY IN ACUTE AND CHRONIC VIRAL HEPATITIS В
title_full	FEATURES OF CELLULAR AND HUMORAL IMMUNITY IN ACUTE AND CHRONIC VIRAL HEPATITIS В
title_fullStr	FEATURES OF CELLULAR AND HUMORAL IMMUNITY IN ACUTE AND CHRONIC VIRAL HEPATITIS В
title_full_unstemmed	FEATURES OF CELLULAR AND HUMORAL IMMUNITY IN ACUTE AND CHRONIC VIRAL HEPATITIS В
title_sort	features of cellular and humoral immunity in acute and chronic viral hepatitis в
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2012
url	https://doaj.org/article/f42c69fca70a4b6b845a167cc12dddcc
work_keys_str_mv	AT agborisov featuresofcellularandhumoralimmunityinacuteandchronicviralhepatitisv AT aasavchenko featuresofcellularandhumoralimmunityinacuteandchronicviralhepatitisv
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FEATURES OF CELLULAR AND HUMORAL IMMUNITY IN ACUTE AND CHRONIC VIRAL HEPATITIS В

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