Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

On the electrocardiogram, the PR interval reflects conduction from the atria to ventricles and also serves as risk indicator of cardiovascular morbidity and mortality. Here, the authors perform genome-wide meta-analyses for PR interval in multiple ancestries and identify 141 previously unreported ge...

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Autores principales: Ioanna Ntalla, Lu-Chen Weng, James H. Cartwright, Amelia Weber Hall, Gardar Sveinbjornsson, Nathan R. Tucker, Seung Hoan Choi, Mark D. Chaffin, Carolina Roselli, Michael R. Barnes, Borbala Mifsud, Helen R. Warren, Caroline Hayward, Jonathan Marten, James J. Cranley, Maria Pina Concas, Paolo Gasparini, Thibaud Boutin, Ivana Kolcic, Ozren Polasek, Igor Rudan, Nathalia M. Araujo, Maria Fernanda Lima-Costa, Antonio Luiz P. Ribeiro, Renan P. Souza, Eduardo Tarazona-Santos, Vilmantas Giedraitis, Erik Ingelsson, Anubha Mahajan, Andrew P. Morris, Fabiola Del Greco M, Luisa Foco, Martin Gögele, Andrew A. Hicks, James P. Cook, Lars Lind, Cecilia M. Lindgren, Johan Sundström, Christopher P. Nelson, Muhammad B. Riaz, Nilesh J. Samani, Gianfranco Sinagra, Sheila Ulivi, Mika Kähönen, Pashupati P. Mishra, Nina Mononen, Kjell Nikus, Mark J. Caulfield, Anna Dominiczak, Sandosh Padmanabhan, May E. Montasser, Jeff R. O’Connell, Kathleen Ryan, Alan R. Shuldiner, Stefanie Aeschbacher, David Conen, Lorenz Risch, Sébastien Thériault, Nina Hutri-Kähönen, Terho Lehtimäki, Leo-Pekka Lyytikäinen, Olli T. Raitakari, Catriona L. K. Barnes, Harry Campbell, Peter K. Joshi, James F. Wilson, Aaron Isaacs, Jan A. Kors, Cornelia M. van Duijn, Paul L. Huang, Vilmundur Gudnason, Tamara B. Harris, Lenore J. Launer, Albert V. Smith, Erwin P. Bottinger, Ruth J. F. Loos, Girish N. Nadkarni, Michael H. Preuss, Adolfo Correa, Hao Mei, James Wilson, Thomas Meitinger, Martina Müller-Nurasyid, Annette Peters, Melanie Waldenberger, Massimo Mangino, Timothy D. Spector, Michiel Rienstra, Yordi J. van de Vegte, Pim van der Harst, Niek Verweij, Stefan Kääb, Katharina Schramm, Moritz F. Sinner, Konstantin Strauch, Michael J. Cutler, Diane Fatkin, Barry London, Morten Olesen, Dan M. Roden, M. Benjamin Shoemaker, J. Gustav Smith, Mary L. Biggs, Joshua C. Bis, Jennifer A. Brody, Bruce M. Psaty, Kenneth Rice, Nona Sotoodehnia, Alessandro De Grandi, Christian Fuchsberger, Cristian Pattaro, Peter P. Pramstaller, Ian Ford, J. Wouter Jukema, Peter W. Macfarlane, Stella Trompet, Marcus Dörr, Stephan B. Felix, Uwe Völker, Stefan Weiss, Aki S. Havulinna, Antti Jula, Katri Sääksjärvi, Veikko Salomaa, Xiuqing Guo, Susan R. Heckbert, Henry J. Lin, Jerome I. Rotter, Kent D. Taylor, Jie Yao, Renée de Mutsert, Arie C. Maan, Dennis O. Mook-Kanamori, Raymond Noordam, Francesco Cucca, Jun Ding, Edward G. Lakatta, Yong Qian, Kirill V. Tarasov, Daniel Levy, Honghuang Lin, Christopher H. Newton-Cheh, Kathryn L. Lunetta, Alison D. Murray, David J. Porteous, Blair H. Smith, Bruno H. Stricker, André Uitterlinden, Marten E. van den Berg, Jeffrey Haessler, Rebecca D. Jackson, Charles Kooperberg, Ulrike Peters, Alexander P. Reiner, Eric A. Whitsel, Alvaro Alonso, Dan E. Arking, Eric Boerwinkle, Georg B. Ehret, Elsayed Z. Soliman, Christy L. Avery, Stephanie M. Gogarten, Kathleen F. Kerr, Cathy C. Laurie, Amanda A. Seyerle, Adrienne Stilp, Solmaz Assa, M. Abdullah Said, M. Yldau van der Ende, Pier D. Lambiase, Michele Orini, Julia Ramirez, Stefan Van Duijvenboden, David O. Arnar, Daniel F. Gudbjartsson, Hilma Holm, Patrick Sulem, Gudmar Thorleifsson, Rosa B. Thorolfsdottir, Unnur Thorsteinsdottir, Emelia J. Benjamin, Andrew Tinker, Kari Stefansson, Patrick T. Ellinor, Yalda Jamshidi, Steven A. Lubitz, Patricia B. Munroe
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spelling oai:doaj.org-article:f435c44c244442da8097cb2f6793771f2021-12-02T16:51:25ZMulti-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction10.1038/s41467-020-15706-x2041-1723https://doaj.org/article/f435c44c244442da8097cb2f6793771f2020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15706-xhttps://doaj.org/toc/2041-1723On the electrocardiogram, the PR interval reflects conduction from the atria to ventricles and also serves as risk indicator of cardiovascular morbidity and mortality. Here, the authors perform genome-wide meta-analyses for PR interval in multiple ancestries and identify 141 previously unreported genetic loci.Ioanna NtallaLu-Chen WengJames H. CartwrightAmelia Weber HallGardar SveinbjornssonNathan R. TuckerSeung Hoan ChoiMark D. ChaffinCarolina RoselliMichael R. BarnesBorbala MifsudHelen R. WarrenCaroline HaywardJonathan MartenJames J. CranleyMaria Pina ConcasPaolo GaspariniThibaud BoutinIvana KolcicOzren PolasekIgor RudanNathalia M. AraujoMaria Fernanda Lima-CostaAntonio Luiz P. RibeiroRenan P. SouzaEduardo Tarazona-SantosVilmantas GiedraitisErik IngelssonAnubha MahajanAndrew P. MorrisFabiola Del Greco MLuisa FocoMartin GögeleAndrew A. HicksJames P. CookLars LindCecilia M. LindgrenJohan SundströmChristopher P. NelsonMuhammad B. RiazNilesh J. SamaniGianfranco SinagraSheila UliviMika KähönenPashupati P. MishraNina MononenKjell NikusMark J. CaulfieldAnna DominiczakSandosh PadmanabhanMay E. MontasserJeff R. O’ConnellKathleen RyanAlan R. ShuldinerStefanie AeschbacherDavid ConenLorenz RischSébastien ThériaultNina Hutri-KähönenTerho LehtimäkiLeo-Pekka LyytikäinenOlli T. RaitakariCatriona L. K. BarnesHarry CampbellPeter K. JoshiJames F. WilsonAaron IsaacsJan A. KorsCornelia M. van DuijnPaul L. HuangVilmundur GudnasonTamara B. HarrisLenore J. LaunerAlbert V. SmithErwin P. BottingerRuth J. F. LoosGirish N. NadkarniMichael H. PreussAdolfo CorreaHao MeiJames WilsonThomas MeitingerMartina Müller-NurasyidAnnette PetersMelanie WaldenbergerMassimo ManginoTimothy D. SpectorMichiel RienstraYordi J. van de VegtePim van der HarstNiek VerweijStefan KääbKatharina SchrammMoritz F. SinnerKonstantin StrauchMichael J. CutlerDiane FatkinBarry LondonMorten OlesenDan M. RodenM. Benjamin ShoemakerJ. Gustav SmithMary L. BiggsJoshua C. BisJennifer A. BrodyBruce M. PsatyKenneth RiceNona SotoodehniaAlessandro De GrandiChristian FuchsbergerCristian PattaroPeter P. PramstallerIan FordJ. Wouter JukemaPeter W. MacfarlaneStella TrompetMarcus DörrStephan B. FelixUwe VölkerStefan WeissAki S. HavulinnaAntti JulaKatri SääksjärviVeikko SalomaaXiuqing GuoSusan R. HeckbertHenry J. LinJerome I. RotterKent D. TaylorJie YaoRenée de MutsertArie C. MaanDennis O. Mook-KanamoriRaymond NoordamFrancesco CuccaJun DingEdward G. LakattaYong QianKirill V. TarasovDaniel LevyHonghuang LinChristopher H. Newton-ChehKathryn L. LunettaAlison D. MurrayDavid J. PorteousBlair H. SmithBruno H. StrickerAndré UitterlindenMarten E. van den BergJeffrey HaesslerRebecca D. JacksonCharles KooperbergUlrike PetersAlexander P. ReinerEric A. WhitselAlvaro AlonsoDan E. ArkingEric BoerwinkleGeorg B. EhretElsayed Z. SolimanChristy L. AveryStephanie M. GogartenKathleen F. KerrCathy C. LaurieAmanda A. SeyerleAdrienne StilpSolmaz AssaM. Abdullah SaidM. Yldau van der EndePier D. LambiaseMichele OriniJulia RamirezStefan Van DuijvenbodenDavid O. ArnarDaniel F. GudbjartssonHilma HolmPatrick SulemGudmar ThorleifssonRosa B. ThorolfsdottirUnnur ThorsteinsdottirEmelia J. BenjaminAndrew TinkerKari StefanssonPatrick T. EllinorYalda JamshidiSteven A. LubitzPatricia B. MunroeNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ioanna Ntalla
Lu-Chen Weng
James H. Cartwright
Amelia Weber Hall
Gardar Sveinbjornsson
Nathan R. Tucker
Seung Hoan Choi
Mark D. Chaffin
Carolina Roselli
Michael R. Barnes
Borbala Mifsud
Helen R. Warren
Caroline Hayward
Jonathan Marten
James J. Cranley
Maria Pina Concas
Paolo Gasparini
Thibaud Boutin
Ivana Kolcic
Ozren Polasek
Igor Rudan
Nathalia M. Araujo
Maria Fernanda Lima-Costa
Antonio Luiz P. Ribeiro
Renan P. Souza
Eduardo Tarazona-Santos
Vilmantas Giedraitis
Erik Ingelsson
Anubha Mahajan
Andrew P. Morris
Fabiola Del Greco M
Luisa Foco
Martin Gögele
Andrew A. Hicks
James P. Cook
Lars Lind
Cecilia M. Lindgren
Johan Sundström
Christopher P. Nelson
Muhammad B. Riaz
Nilesh J. Samani
Gianfranco Sinagra
Sheila Ulivi
Mika Kähönen
Pashupati P. Mishra
Nina Mononen
Kjell Nikus
Mark J. Caulfield
Anna Dominiczak
Sandosh Padmanabhan
May E. Montasser
Jeff R. O’Connell
Kathleen Ryan
Alan R. Shuldiner
Stefanie Aeschbacher
David Conen
Lorenz Risch
Sébastien Thériault
Nina Hutri-Kähönen
Terho Lehtimäki
Leo-Pekka Lyytikäinen
Olli T. Raitakari
Catriona L. K. Barnes
Harry Campbell
Peter K. Joshi
James F. Wilson
Aaron Isaacs
Jan A. Kors
Cornelia M. van Duijn
Paul L. Huang
Vilmundur Gudnason
Tamara B. Harris
Lenore J. Launer
Albert V. Smith
Erwin P. Bottinger
Ruth J. F. Loos
Girish N. Nadkarni
Michael H. Preuss
Adolfo Correa
Hao Mei
James Wilson
Thomas Meitinger
Martina Müller-Nurasyid
Annette Peters
Melanie Waldenberger
Massimo Mangino
Timothy D. Spector
Michiel Rienstra
Yordi J. van de Vegte
Pim van der Harst
Niek Verweij
Stefan Kääb
Katharina Schramm
Moritz F. Sinner
Konstantin Strauch
Michael J. Cutler
Diane Fatkin
Barry London
Morten Olesen
Dan M. Roden
M. Benjamin Shoemaker
J. Gustav Smith
Mary L. Biggs
Joshua C. Bis
Jennifer A. Brody
Bruce M. Psaty
Kenneth Rice
Nona Sotoodehnia
Alessandro De Grandi
Christian Fuchsberger
Cristian Pattaro
Peter P. Pramstaller
Ian Ford
J. Wouter Jukema
Peter W. Macfarlane
Stella Trompet
Marcus Dörr
Stephan B. Felix
Uwe Völker
Stefan Weiss
Aki S. Havulinna
Antti Jula
Katri Sääksjärvi
Veikko Salomaa
Xiuqing Guo
Susan R. Heckbert
Henry J. Lin
Jerome I. Rotter
Kent D. Taylor
Jie Yao
Renée de Mutsert
Arie C. Maan
Dennis O. Mook-Kanamori
Raymond Noordam
Francesco Cucca
Jun Ding
Edward G. Lakatta
Yong Qian
Kirill V. Tarasov
Daniel Levy
Honghuang Lin
Christopher H. Newton-Cheh
Kathryn L. Lunetta
Alison D. Murray
David J. Porteous
Blair H. Smith
Bruno H. Stricker
André Uitterlinden
Marten E. van den Berg
Jeffrey Haessler
Rebecca D. Jackson
Charles Kooperberg
Ulrike Peters
Alexander P. Reiner
Eric A. Whitsel
Alvaro Alonso
Dan E. Arking
Eric Boerwinkle
Georg B. Ehret
Elsayed Z. Soliman
Christy L. Avery
Stephanie M. Gogarten
Kathleen F. Kerr
Cathy C. Laurie
Amanda A. Seyerle
Adrienne Stilp
Solmaz Assa
M. Abdullah Said
M. Yldau van der Ende
Pier D. Lambiase
Michele Orini
Julia Ramirez
Stefan Van Duijvenboden
David O. Arnar
Daniel F. Gudbjartsson
Hilma Holm
Patrick Sulem
Gudmar Thorleifsson
Rosa B. Thorolfsdottir
Unnur Thorsteinsdottir
Emelia J. Benjamin
Andrew Tinker
Kari Stefansson
Patrick T. Ellinor
Yalda Jamshidi
Steven A. Lubitz
Patricia B. Munroe
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction
description On the electrocardiogram, the PR interval reflects conduction from the atria to ventricles and also serves as risk indicator of cardiovascular morbidity and mortality. Here, the authors perform genome-wide meta-analyses for PR interval in multiple ancestries and identify 141 previously unreported genetic loci.
format article
author Ioanna Ntalla
Lu-Chen Weng
James H. Cartwright
Amelia Weber Hall
Gardar Sveinbjornsson
Nathan R. Tucker
Seung Hoan Choi
Mark D. Chaffin
Carolina Roselli
Michael R. Barnes
Borbala Mifsud
Helen R. Warren
Caroline Hayward
Jonathan Marten
James J. Cranley
Maria Pina Concas
Paolo Gasparini
Thibaud Boutin
Ivana Kolcic
Ozren Polasek
Igor Rudan
Nathalia M. Araujo
Maria Fernanda Lima-Costa
Antonio Luiz P. Ribeiro
Renan P. Souza
Eduardo Tarazona-Santos
Vilmantas Giedraitis
Erik Ingelsson
Anubha Mahajan
Andrew P. Morris
Fabiola Del Greco M
Luisa Foco
Martin Gögele
Andrew A. Hicks
James P. Cook
Lars Lind
Cecilia M. Lindgren
Johan Sundström
Christopher P. Nelson
Muhammad B. Riaz
Nilesh J. Samani
Gianfranco Sinagra
Sheila Ulivi
Mika Kähönen
Pashupati P. Mishra
Nina Mononen
Kjell Nikus
Mark J. Caulfield
Anna Dominiczak
Sandosh Padmanabhan
May E. Montasser
Jeff R. O’Connell
Kathleen Ryan
Alan R. Shuldiner
Stefanie Aeschbacher
David Conen
Lorenz Risch
Sébastien Thériault
Nina Hutri-Kähönen
Terho Lehtimäki
Leo-Pekka Lyytikäinen
Olli T. Raitakari
Catriona L. K. Barnes
Harry Campbell
Peter K. Joshi
James F. Wilson
Aaron Isaacs
Jan A. Kors
Cornelia M. van Duijn
Paul L. Huang
Vilmundur Gudnason
Tamara B. Harris
Lenore J. Launer
Albert V. Smith
Erwin P. Bottinger
Ruth J. F. Loos
Girish N. Nadkarni
Michael H. Preuss
Adolfo Correa
Hao Mei
James Wilson
Thomas Meitinger
Martina Müller-Nurasyid
Annette Peters
Melanie Waldenberger
Massimo Mangino
Timothy D. Spector
Michiel Rienstra
Yordi J. van de Vegte
Pim van der Harst
Niek Verweij
Stefan Kääb
Katharina Schramm
Moritz F. Sinner
Konstantin Strauch
Michael J. Cutler
Diane Fatkin
Barry London
Morten Olesen
Dan M. Roden
M. Benjamin Shoemaker
J. Gustav Smith
Mary L. Biggs
Joshua C. Bis
Jennifer A. Brody
Bruce M. Psaty
Kenneth Rice
Nona Sotoodehnia
Alessandro De Grandi
Christian Fuchsberger
Cristian Pattaro
Peter P. Pramstaller
Ian Ford
J. Wouter Jukema
Peter W. Macfarlane
Stella Trompet
Marcus Dörr
Stephan B. Felix
Uwe Völker
Stefan Weiss
Aki S. Havulinna
Antti Jula
Katri Sääksjärvi
Veikko Salomaa
Xiuqing Guo
Susan R. Heckbert
Henry J. Lin
Jerome I. Rotter
Kent D. Taylor
Jie Yao
Renée de Mutsert
Arie C. Maan
Dennis O. Mook-Kanamori
Raymond Noordam
Francesco Cucca
Jun Ding
Edward G. Lakatta
Yong Qian
Kirill V. Tarasov
Daniel Levy
Honghuang Lin
Christopher H. Newton-Cheh
Kathryn L. Lunetta
Alison D. Murray
David J. Porteous
Blair H. Smith
Bruno H. Stricker
André Uitterlinden
Marten E. van den Berg
Jeffrey Haessler
Rebecca D. Jackson
Charles Kooperberg
Ulrike Peters
Alexander P. Reiner
Eric A. Whitsel
Alvaro Alonso
Dan E. Arking
Eric Boerwinkle
Georg B. Ehret
Elsayed Z. Soliman
Christy L. Avery
Stephanie M. Gogarten
Kathleen F. Kerr
Cathy C. Laurie
Amanda A. Seyerle
Adrienne Stilp
Solmaz Assa
M. Abdullah Said
M. Yldau van der Ende
Pier D. Lambiase
Michele Orini
Julia Ramirez
Stefan Van Duijvenboden
David O. Arnar
Daniel F. Gudbjartsson
Hilma Holm
Patrick Sulem
Gudmar Thorleifsson
Rosa B. Thorolfsdottir
Unnur Thorsteinsdottir
Emelia J. Benjamin
Andrew Tinker
Kari Stefansson
Patrick T. Ellinor
Yalda Jamshidi
Steven A. Lubitz
Patricia B. Munroe
author_facet Ioanna Ntalla
Lu-Chen Weng
James H. Cartwright
Amelia Weber Hall
Gardar Sveinbjornsson
Nathan R. Tucker
Seung Hoan Choi
Mark D. Chaffin
Carolina Roselli
Michael R. Barnes
Borbala Mifsud
Helen R. Warren
Caroline Hayward
Jonathan Marten
James J. Cranley
Maria Pina Concas
Paolo Gasparini
Thibaud Boutin
Ivana Kolcic
Ozren Polasek
Igor Rudan
Nathalia M. Araujo
Maria Fernanda Lima-Costa
Antonio Luiz P. Ribeiro
Renan P. Souza
Eduardo Tarazona-Santos
Vilmantas Giedraitis
Erik Ingelsson
Anubha Mahajan
Andrew P. Morris
Fabiola Del Greco M
Luisa Foco
Martin Gögele
Andrew A. Hicks
James P. Cook
Lars Lind
Cecilia M. Lindgren
Johan Sundström
Christopher P. Nelson
Muhammad B. Riaz
Nilesh J. Samani
Gianfranco Sinagra
Sheila Ulivi
Mika Kähönen
Pashupati P. Mishra
Nina Mononen
Kjell Nikus
Mark J. Caulfield
Anna Dominiczak
Sandosh Padmanabhan
May E. Montasser
Jeff R. O’Connell
Kathleen Ryan
Alan R. Shuldiner
Stefanie Aeschbacher
David Conen
Lorenz Risch
Sébastien Thériault
Nina Hutri-Kähönen
Terho Lehtimäki
Leo-Pekka Lyytikäinen
Olli T. Raitakari
Catriona L. K. Barnes
Harry Campbell
Peter K. Joshi
James F. Wilson
Aaron Isaacs
Jan A. Kors
Cornelia M. van Duijn
Paul L. Huang
Vilmundur Gudnason
Tamara B. Harris
Lenore J. Launer
Albert V. Smith
Erwin P. Bottinger
Ruth J. F. Loos
Girish N. Nadkarni
Michael H. Preuss
Adolfo Correa
Hao Mei
James Wilson
Thomas Meitinger
Martina Müller-Nurasyid
Annette Peters
Melanie Waldenberger
Massimo Mangino
Timothy D. Spector
Michiel Rienstra
Yordi J. van de Vegte
Pim van der Harst
Niek Verweij
Stefan Kääb
Katharina Schramm
Moritz F. Sinner
Konstantin Strauch
Michael J. Cutler
Diane Fatkin
Barry London
Morten Olesen
Dan M. Roden
M. Benjamin Shoemaker
J. Gustav Smith
Mary L. Biggs
Joshua C. Bis
Jennifer A. Brody
Bruce M. Psaty
Kenneth Rice
Nona Sotoodehnia
Alessandro De Grandi
Christian Fuchsberger
Cristian Pattaro
Peter P. Pramstaller
Ian Ford
J. Wouter Jukema
Peter W. Macfarlane
Stella Trompet
Marcus Dörr
Stephan B. Felix
Uwe Völker
Stefan Weiss
Aki S. Havulinna
Antti Jula
Katri Sääksjärvi
Veikko Salomaa
Xiuqing Guo
Susan R. Heckbert
Henry J. Lin
Jerome I. Rotter
Kent D. Taylor
Jie Yao
Renée de Mutsert
Arie C. Maan
Dennis O. Mook-Kanamori
Raymond Noordam
Francesco Cucca
Jun Ding
Edward G. Lakatta
Yong Qian
Kirill V. Tarasov
Daniel Levy
Honghuang Lin
Christopher H. Newton-Cheh
Kathryn L. Lunetta
Alison D. Murray
David J. Porteous
Blair H. Smith
Bruno H. Stricker
André Uitterlinden
Marten E. van den Berg
Jeffrey Haessler
Rebecca D. Jackson
Charles Kooperberg
Ulrike Peters
Alexander P. Reiner
Eric A. Whitsel
Alvaro Alonso
Dan E. Arking
Eric Boerwinkle
Georg B. Ehret
Elsayed Z. Soliman
Christy L. Avery
Stephanie M. Gogarten
Kathleen F. Kerr
Cathy C. Laurie
Amanda A. Seyerle
Adrienne Stilp
Solmaz Assa
M. Abdullah Said
M. Yldau van der Ende
Pier D. Lambiase
Michele Orini
Julia Ramirez
Stefan Van Duijvenboden
David O. Arnar
Daniel F. Gudbjartsson
Hilma Holm
Patrick Sulem
Gudmar Thorleifsson
Rosa B. Thorolfsdottir
Unnur Thorsteinsdottir
Emelia J. Benjamin
Andrew Tinker
Kari Stefansson
Patrick T. Ellinor
Yalda Jamshidi
Steven A. Lubitz
Patricia B. Munroe
author_sort Ioanna Ntalla
title Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction
title_short Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction
title_full Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction
title_fullStr Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction
title_full_unstemmed Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction
title_sort multi-ancestry gwas of the electrocardiographic pr interval identifies 202 loci underlying cardiac conduction
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/f435c44c244442da8097cb2f6793771f
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AT vilmantasgiedraitis multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT erikingelsson multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT anubhamahajan multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT andrewpmorris multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT fabioladelgrecom multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT luisafoco multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT martingogele multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT andrewahicks multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT jamespcook multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT larslind multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT ceciliamlindgren multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT johansundstrom multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT christopherpnelson multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT muhammadbriaz multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT nileshjsamani multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT gianfrancosinagra multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT sheilaulivi multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT mikakahonen multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT pashupatipmishra multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT ninamononen multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT kjellnikus multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT markjcaulfield multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT annadominiczak multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT sandoshpadmanabhan multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT mayemontasser multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT jeffroconnell multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT kathleenryan multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT alanrshuldiner multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT stefanieaeschbacher multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT davidconen multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT lorenzrisch multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT sebastientheriault multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT ninahutrikahonen multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT terholehtimaki multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT leopekkalyytikainen multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT ollitraitakari multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT catrionalkbarnes multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT harrycampbell multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT peterkjoshi multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT jamesfwilson multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT aaronisaacs multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT janakors multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT corneliamvanduijn multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT paullhuang multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT vilmundurgudnason multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT tamarabharris multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT lenorejlauner multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT albertvsmith multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT erwinpbottinger multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT ruthjfloos multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT girishnnadkarni multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT michaelhpreuss multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT adolfocorrea multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT haomei multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT jameswilson multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT thomasmeitinger multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT martinamullernurasyid multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT annettepeters multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT melaniewaldenberger multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT massimomangino multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT timothydspector multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT michielrienstra multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT yordijvandevegte multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT pimvanderharst multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT niekverweij multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT stefankaab multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT katharinaschramm multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT moritzfsinner multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT konstantinstrauch multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT michaeljcutler multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT dianefatkin multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT barrylondon multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT mortenolesen multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT danmroden multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT mbenjaminshoemaker multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT jgustavsmith multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT marylbiggs multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT joshuacbis multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT jenniferabrody multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT brucempsaty multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT kennethrice multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT nonasotoodehnia multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT alessandrodegrandi multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT christianfuchsberger multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT cristianpattaro multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT peterppramstaller multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT ianford multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT jwouterjukema multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT peterwmacfarlane multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT stellatrompet multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT marcusdorr multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT stephanbfelix multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT uwevolker multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT stefanweiss multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT akishavulinna multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT anttijula multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT katrisaaksjarvi multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT veikkosalomaa multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT xiuqingguo multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT susanrheckbert multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT henryjlin multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT jeromeirotter multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT kentdtaylor multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT jieyao multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT reneedemutsert multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT ariecmaan multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT dennisomookkanamori multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT raymondnoordam multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT francescocucca multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT junding multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT edwardglakatta multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT yongqian multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT kirillvtarasov multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT daniellevy multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT honghuanglin multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT christopherhnewtoncheh multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT kathrynllunetta multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT alisondmurray multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT davidjporteous multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT blairhsmith multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT brunohstricker multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT andreuitterlinden multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT martenevandenberg multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT jeffreyhaessler multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT rebeccadjackson multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT charleskooperberg multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT ulrikepeters multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT alexanderpreiner multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT ericawhitsel multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT alvaroalonso multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT danearking multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT ericboerwinkle multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT georgbehret multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT elsayedzsoliman multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT christylavery multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT stephaniemgogarten multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT kathleenfkerr multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT cathyclaurie multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT amandaaseyerle multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT adriennestilp multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT solmazassa multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT mabdullahsaid multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT myldauvanderende multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT pierdlambiase multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT micheleorini multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT juliaramirez multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT stefanvanduijvenboden multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT davidoarnar multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT danielfgudbjartsson multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT hilmaholm multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT patricksulem multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT gudmarthorleifsson multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT rosabthorolfsdottir multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT unnurthorsteinsdottir multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT emeliajbenjamin multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT andrewtinker multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT karistefansson multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT patricktellinor multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT yaldajamshidi multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT stevenalubitz multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
AT patriciabmunroe multiancestrygwasoftheelectrocardiographicprintervalidentifies202lociunderlyingcardiacconduction
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