Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation
PRMT1 is an arginine methyltransferase involved in a variety of cell functions. Here the authors delete PRMT1 specifically in mature B cells to show the importance of arginine methylation for B cell proliferation, differentiation and survival, and thereby for humoral immunity.
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Nature Portfolio
2017
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oai:doaj.org-article:f43684f73c68477f96647f41ab02832e2021-12-02T15:38:46ZArginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation10.1038/s41467-017-01009-12041-1723https://doaj.org/article/f43684f73c68477f96647f41ab02832e2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01009-1https://doaj.org/toc/2041-1723PRMT1 is an arginine methyltransferase involved in a variety of cell functions. Here the authors delete PRMT1 specifically in mature B cells to show the importance of arginine methylation for B cell proliferation, differentiation and survival, and thereby for humoral immunity.Simona InfantinoAmanda LightKristy O’DonnellVanessa BryantDanielle T. AveryMichael ElliottStuart G. TangyeGabrielle BelzFabienne MackayStephane RichardDavid TarlintonNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Simona Infantino Amanda Light Kristy O’Donnell Vanessa Bryant Danielle T. Avery Michael Elliott Stuart G. Tangye Gabrielle Belz Fabienne Mackay Stephane Richard David Tarlinton Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation |
| description |
PRMT1 is an arginine methyltransferase involved in a variety of cell functions. Here the authors delete PRMT1 specifically in mature B cells to show the importance of arginine methylation for B cell proliferation, differentiation and survival, and thereby for humoral immunity. |
| format |
article |
| author |
Simona Infantino Amanda Light Kristy O’Donnell Vanessa Bryant Danielle T. Avery Michael Elliott Stuart G. Tangye Gabrielle Belz Fabienne Mackay Stephane Richard David Tarlinton |
| author_facet |
Simona Infantino Amanda Light Kristy O’Donnell Vanessa Bryant Danielle T. Avery Michael Elliott Stuart G. Tangye Gabrielle Belz Fabienne Mackay Stephane Richard David Tarlinton |
| author_sort |
Simona Infantino |
| title |
Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation |
| title_short |
Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation |
| title_full |
Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation |
| title_fullStr |
Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation |
| title_full_unstemmed |
Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation |
| title_sort |
arginine methylation catalyzed by prmt1 is required for b cell activation and differentiation |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/f43684f73c68477f96647f41ab02832e |
| work_keys_str_mv |
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| _version_ |
1718386086509543424 |