Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation

Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation

PRMT1 is an arginine methyltransferase involved in a variety of cell functions. Here the authors delete PRMT1 specifically in mature B cells to show the importance of arginine methylation for B cell proliferation, differentiation and survival, and thereby for humoral immunity.

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Detalles Bibliográficos
Autores principales: Simona Infantino, Amanda Light, Kristy O’Donnell, Vanessa Bryant, Danielle T. Avery, Michael Elliott, Stuart G. Tangye, Gabrielle Belz, Fabienne Mackay, Stephane Richard, David Tarlinton
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/f43684f73c68477f96647f41ab02832e
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