NEUROIMMUNOLOGICAL ASPECTS OF PATHOGENESIS IN CHILDREN’S CEREBRAL PALSY
Аbstract. Present review article considers neuroimmunological issues in pathogenesis of infantile cerebral paralysis (ICP). Various factors of immune system and cytokine regulation network (including TNFα, interleukins) have been shown to participate in development of pathological events...
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2014
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oai:doaj.org-article:f449ee2c606a4c5d99a30032ac5c44e22021-11-18T08:03:41ZNEUROIMMUNOLOGICAL ASPECTS OF PATHOGENESIS IN CHILDREN’S CEREBRAL PALSY1563-06252313-741X10.15789/1563-0625-2011-2-3-115-120https://doaj.org/article/f449ee2c606a4c5d99a30032ac5c44e22014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/450https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XАbstract. Present review article considers neuroimmunological issues in pathogenesis of infantile cerebral paralysis (ICP). Various factors of immune system and cytokine regulation network (including TNFα, interleukins) have been shown to participate in development of pathological events in patients with periventricular leukomalacia which result into evolving ICP. Selective cytotoxic activity of TNFα was analyzed as a factor in development of continuous chronic process. A role of immunopathological events for development of cytogenetic rearrangements in peripheral blood cells is proposed. (Med. Immunol., 2011, vol. 13, N 2-3, pp 115-120)L. Z. GaysinaD. D. GaynetdinovaR. F. KhakimovaSPb RAACIarticleinfantile cerebral palsyperiventricular leukomalacianeuroimmunologic mechanismstumor necrosis factor alphacytokinesImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 13, Iss 2-3, Pp 115-120 (2014) |
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DOAJ |
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infantile cerebral palsy periventricular leukomalacia neuroimmunologic mechanisms tumor necrosis factor alpha cytokines Immunologic diseases. Allergy RC581-607 |
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infantile cerebral palsy periventricular leukomalacia neuroimmunologic mechanisms tumor necrosis factor alpha cytokines Immunologic diseases. Allergy RC581-607 L. Z. Gaysina D. D. Gaynetdinova R. F. Khakimova NEUROIMMUNOLOGICAL ASPECTS OF PATHOGENESIS IN CHILDREN’S CEREBRAL PALSY |
description |
Аbstract. Present review article considers neuroimmunological issues in pathogenesis of infantile cerebral paralysis (ICP). Various factors of immune system and cytokine regulation network (including TNFα, interleukins) have been shown to participate in development of pathological events in patients with periventricular leukomalacia which result into evolving ICP. Selective cytotoxic activity of TNFα was analyzed as a factor in development of continuous chronic process. A role of immunopathological events for development of cytogenetic rearrangements in peripheral blood cells is proposed. (Med. Immunol., 2011, vol. 13, N 2-3, pp 115-120) |
format |
article |
author |
L. Z. Gaysina D. D. Gaynetdinova R. F. Khakimova |
author_facet |
L. Z. Gaysina D. D. Gaynetdinova R. F. Khakimova |
author_sort |
L. Z. Gaysina |
title |
NEUROIMMUNOLOGICAL ASPECTS OF PATHOGENESIS IN CHILDREN’S CEREBRAL PALSY |
title_short |
NEUROIMMUNOLOGICAL ASPECTS OF PATHOGENESIS IN CHILDREN’S CEREBRAL PALSY |
title_full |
NEUROIMMUNOLOGICAL ASPECTS OF PATHOGENESIS IN CHILDREN’S CEREBRAL PALSY |
title_fullStr |
NEUROIMMUNOLOGICAL ASPECTS OF PATHOGENESIS IN CHILDREN’S CEREBRAL PALSY |
title_full_unstemmed |
NEUROIMMUNOLOGICAL ASPECTS OF PATHOGENESIS IN CHILDREN’S CEREBRAL PALSY |
title_sort |
neuroimmunological aspects of pathogenesis in children’s cerebral palsy |
publisher |
SPb RAACI |
publishDate |
2014 |
url |
https://doaj.org/article/f449ee2c606a4c5d99a30032ac5c44e2 |
work_keys_str_mv |
AT lzgaysina neuroimmunologicalaspectsofpathogenesisinchildrenscerebralpalsy AT ddgaynetdinova neuroimmunologicalaspectsofpathogenesisinchildrenscerebralpalsy AT rfkhakimova neuroimmunologicalaspectsofpathogenesisinchildrenscerebralpalsy |
_version_ |
1718422518374596608 |