NEUROIMMUNOLOGICAL ASPECTS OF PATHOGENESIS IN CHILDREN’S CEREBRAL PALSY

Аbstract. Present review article considers neuroimmunological issues in pathogenesis of infantile cerebral paralysis  (ICP).  Various  factors  of  immune  system  and  cytokine  regulation  network  (including  TNFα, interleukins) have been shown to participate in development of pathological events...

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Autores principales: L. Z. Gaysina, D. D. Gaynetdinova, R. F. Khakimova
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Lenguaje:RU
Publicado: SPb RAACI 2014
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Acceso en línea:https://doaj.org/article/f449ee2c606a4c5d99a30032ac5c44e2
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spelling oai:doaj.org-article:f449ee2c606a4c5d99a30032ac5c44e22021-11-18T08:03:41ZNEUROIMMUNOLOGICAL ASPECTS OF PATHOGENESIS IN CHILDREN’S CEREBRAL PALSY1563-06252313-741X10.15789/1563-0625-2011-2-3-115-120https://doaj.org/article/f449ee2c606a4c5d99a30032ac5c44e22014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/450https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XАbstract. Present review article considers neuroimmunological issues in pathogenesis of infantile cerebral paralysis  (ICP).  Various  factors  of  immune  system  and  cytokine  regulation  network  (including  TNFα, interleukins) have been shown to participate in development of pathological events in patients with periventricular leukomalacia which result into evolving ICP. Selective cytotoxic activity of TNFα was analyzed as a factor in development of continuous chronic process. A role of immunopathological events for development of cytogenetic rearrangements in peripheral blood cells is proposed. (Med. Immunol., 2011, vol. 13, N 2-3, pp 115-120)L. Z. GaysinaD. D. GaynetdinovaR. F. KhakimovaSPb RAACIarticleinfantile cerebral palsyperiventricular leukomalacianeuroimmunologic mechanismstumor necrosis factor alphacytokinesImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 13, Iss 2-3, Pp 115-120 (2014)
institution DOAJ
collection DOAJ
language RU
topic infantile cerebral palsy
periventricular leukomalacia
neuroimmunologic mechanisms
tumor necrosis factor alpha
cytokines
Immunologic diseases. Allergy
RC581-607
spellingShingle infantile cerebral palsy
periventricular leukomalacia
neuroimmunologic mechanisms
tumor necrosis factor alpha
cytokines
Immunologic diseases. Allergy
RC581-607
L. Z. Gaysina
D. D. Gaynetdinova
R. F. Khakimova
NEUROIMMUNOLOGICAL ASPECTS OF PATHOGENESIS IN CHILDREN’S CEREBRAL PALSY
description Аbstract. Present review article considers neuroimmunological issues in pathogenesis of infantile cerebral paralysis  (ICP).  Various  factors  of  immune  system  and  cytokine  regulation  network  (including  TNFα, interleukins) have been shown to participate in development of pathological events in patients with periventricular leukomalacia which result into evolving ICP. Selective cytotoxic activity of TNFα was analyzed as a factor in development of continuous chronic process. A role of immunopathological events for development of cytogenetic rearrangements in peripheral blood cells is proposed. (Med. Immunol., 2011, vol. 13, N 2-3, pp 115-120)
format article
author L. Z. Gaysina
D. D. Gaynetdinova
R. F. Khakimova
author_facet L. Z. Gaysina
D. D. Gaynetdinova
R. F. Khakimova
author_sort L. Z. Gaysina
title NEUROIMMUNOLOGICAL ASPECTS OF PATHOGENESIS IN CHILDREN’S CEREBRAL PALSY
title_short NEUROIMMUNOLOGICAL ASPECTS OF PATHOGENESIS IN CHILDREN’S CEREBRAL PALSY
title_full NEUROIMMUNOLOGICAL ASPECTS OF PATHOGENESIS IN CHILDREN’S CEREBRAL PALSY
title_fullStr NEUROIMMUNOLOGICAL ASPECTS OF PATHOGENESIS IN CHILDREN’S CEREBRAL PALSY
title_full_unstemmed NEUROIMMUNOLOGICAL ASPECTS OF PATHOGENESIS IN CHILDREN’S CEREBRAL PALSY
title_sort neuroimmunological aspects of pathogenesis in children’s cerebral palsy
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/f449ee2c606a4c5d99a30032ac5c44e2
work_keys_str_mv AT lzgaysina neuroimmunologicalaspectsofpathogenesisinchildrenscerebralpalsy
AT ddgaynetdinova neuroimmunologicalaspectsofpathogenesisinchildrenscerebralpalsy
AT rfkhakimova neuroimmunologicalaspectsofpathogenesisinchildrenscerebralpalsy
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