Diagnostic and Management Strategies of Aspergillus Endophthalmitis: Current Insights

Leopoldo Spadea, Maria Ilaria Giannico University “La Sapienza”, Department of Sense Organs, Eye Clinic, Rome, ItalyCorrespondence: Leopoldo SpadeaHead Eye Clinic, Policlinico Umberto 1, “Sapienza” University of Rome, Via Benozzo Gozzoli 34, Rome 00142, ItalyT...

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Autores principales: Spadea L, Giannico MI
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Lenguaje:EN
Publicado: Dove Medical Press 2019
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spelling oai:doaj.org-article:f44d6baf360e4d1eabf03215b840e96f2021-12-02T08:55:28ZDiagnostic and Management Strategies of Aspergillus Endophthalmitis: Current Insights1177-5483https://doaj.org/article/f44d6baf360e4d1eabf03215b840e96f2019-12-01T00:00:00Zhttps://www.dovepress.com/diagnostic-and-management-strategies-of-aspergillus-endophthalmitis-cu-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Leopoldo Spadea, Maria Ilaria Giannico University “La Sapienza”, Department of Sense Organs, Eye Clinic, Rome, ItalyCorrespondence: Leopoldo SpadeaHead Eye Clinic, Policlinico Umberto 1, “Sapienza” University of Rome, Via Benozzo Gozzoli 34, Rome 00142, ItalyTel +39 06 519 3220Fax +39 06 8865 7818Email leopoldo.spadea@uniroma1.itAbstract: Fungal endophthalmitis is subsequent to endogenous or exogenous infection and represents an important complication of ocular surgery which may lead to significant visual loss and blindness. The prognosis is poor because of delayed diagnosis and limited availability of effective antifungal drugs with good ocular penetration. Furthermore, the critical issue in diagnosing fungal infection of the eye is microbiological identification of the etiologic agent in clinical samples. Aspergillus is among the most frequent isolated organisms in fungal endophthalmitis. Early diagnosis is essential to prevent severe complications and blindness. Treatments include local, systemic and surgical therapeutic strategies. The purpose of the present review is the analysis of the current procedures adopted to promptly diagnose and treat Aspergillus endophthalmitis.Keywords: Aspergillus, endophthalmitis, fungal infection, cataract surgery, ocular mycosesSpadea LGiannico MIDove Medical Pressarticleaspergillusendophthalmitisfungal infectioncataract surgeryocular mycoses.OphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 13, Pp 2573-2582 (2019)
institution DOAJ
collection DOAJ
language EN
topic aspergillus
endophthalmitis
fungal infection
cataract surgery
ocular mycoses.
Ophthalmology
RE1-994
spellingShingle aspergillus
endophthalmitis
fungal infection
cataract surgery
ocular mycoses.
Ophthalmology
RE1-994
Spadea L
Giannico MI
Diagnostic and Management Strategies of Aspergillus Endophthalmitis: Current Insights
description Leopoldo Spadea, Maria Ilaria Giannico University “La Sapienza”, Department of Sense Organs, Eye Clinic, Rome, ItalyCorrespondence: Leopoldo SpadeaHead Eye Clinic, Policlinico Umberto 1, “Sapienza” University of Rome, Via Benozzo Gozzoli 34, Rome 00142, ItalyTel +39 06 519 3220Fax +39 06 8865 7818Email leopoldo.spadea@uniroma1.itAbstract: Fungal endophthalmitis is subsequent to endogenous or exogenous infection and represents an important complication of ocular surgery which may lead to significant visual loss and blindness. The prognosis is poor because of delayed diagnosis and limited availability of effective antifungal drugs with good ocular penetration. Furthermore, the critical issue in diagnosing fungal infection of the eye is microbiological identification of the etiologic agent in clinical samples. Aspergillus is among the most frequent isolated organisms in fungal endophthalmitis. Early diagnosis is essential to prevent severe complications and blindness. Treatments include local, systemic and surgical therapeutic strategies. The purpose of the present review is the analysis of the current procedures adopted to promptly diagnose and treat Aspergillus endophthalmitis.Keywords: Aspergillus, endophthalmitis, fungal infection, cataract surgery, ocular mycoses
format article
author Spadea L
Giannico MI
author_facet Spadea L
Giannico MI
author_sort Spadea L
title Diagnostic and Management Strategies of Aspergillus Endophthalmitis: Current Insights
title_short Diagnostic and Management Strategies of Aspergillus Endophthalmitis: Current Insights
title_full Diagnostic and Management Strategies of Aspergillus Endophthalmitis: Current Insights
title_fullStr Diagnostic and Management Strategies of Aspergillus Endophthalmitis: Current Insights
title_full_unstemmed Diagnostic and Management Strategies of Aspergillus Endophthalmitis: Current Insights
title_sort diagnostic and management strategies of aspergillus endophthalmitis: current insights
publisher Dove Medical Press
publishDate 2019
url https://doaj.org/article/f44d6baf360e4d1eabf03215b840e96f
work_keys_str_mv AT spadeal diagnosticandmanagementstrategiesofaspergillusendophthalmitiscurrentinsights
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