Perimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism: A case report and literature review

Gestational trophoblastic disease (GTD) commonly occurs in reproductive females, but is extremely rare in perimenopausal females. In this study, we reported a case of hydatidiform mole in a 48-year-old perimenopausal female admitted due to a giant uterine mass of 28 weeks’ gestational size. The seru...

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Autores principales:	Wan Yan, Jiang Guoqing, Jin Ying, Hao Zengping
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2021
Materias:	giant hydatidiform mole perimenopausal preeclampsia hyperthyroidism Medicine R
Acceso en línea:	https://doaj.org/article/f45c1848c1684d518311004a4441915a
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spelling	oai:doaj.org-article:f45c1848c1684d518311004a4441915a2021-12-05T14:10:55ZPerimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism: A case report and literature review2391-546310.1515/med-2021-0315https://doaj.org/article/f45c1848c1684d518311004a4441915a2021-07-01T00:00:00Zhttps://doi.org/10.1515/med-2021-0315https://doaj.org/toc/2391-5463Gestational trophoblastic disease (GTD) commonly occurs in reproductive females, but is extremely rare in perimenopausal females. In this study, we reported a case of hydatidiform mole in a 48-year-old perimenopausal female admitted due to a giant uterine mass of 28 weeks’ gestational size. The serum human chorionic gonadotropin (HCG) level ranged from 944 to 1,286 mIU/mL before treatments. The signs of preeclampsia and hyperthyroidism were relatively prominent. Hysterectomy was performed and chemotherapy was scheduled when the serum HCG level remained at a plateau, about 528 mIU/mL. The symptoms of preeclampsia and hyperthyroidism were relieved after treatment. Accordingly, we concluded that GTD could occur in perimenopausal woman and hysterectomy usually is the optimal treatment.Wan YanJiang GuoqingJin YingHao ZengpingDe Gruyterarticlegiant hydatidiform moleperimenopausalpreeclampsiahyperthyroidismMedicineRENOpen Medicine, Vol 16, Iss 1, Pp 1038-1042 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	giant hydatidiform mole perimenopausal preeclampsia hyperthyroidism Medicine R
spellingShingle	giant hydatidiform mole perimenopausal preeclampsia hyperthyroidism Medicine R Wan Yan Jiang Guoqing Jin Ying Hao Zengping Perimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism: A case report and literature review
description	Gestational trophoblastic disease (GTD) commonly occurs in reproductive females, but is extremely rare in perimenopausal females. In this study, we reported a case of hydatidiform mole in a 48-year-old perimenopausal female admitted due to a giant uterine mass of 28 weeks’ gestational size. The serum human chorionic gonadotropin (HCG) level ranged from 944 to 1,286 mIU/mL before treatments. The signs of preeclampsia and hyperthyroidism were relatively prominent. Hysterectomy was performed and chemotherapy was scheduled when the serum HCG level remained at a plateau, about 528 mIU/mL. The symptoms of preeclampsia and hyperthyroidism were relieved after treatment. Accordingly, we concluded that GTD could occur in perimenopausal woman and hysterectomy usually is the optimal treatment.
format	article
author	Wan Yan Jiang Guoqing Jin Ying Hao Zengping
author_facet	Wan Yan Jiang Guoqing Jin Ying Hao Zengping
author_sort	Wan Yan
title	Perimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism: A case report and literature review
title_short	Perimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism: A case report and literature review
title_full	Perimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism: A case report and literature review
title_fullStr	Perimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism: A case report and literature review
title_full_unstemmed	Perimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism: A case report and literature review
title_sort	perimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism: a case report and literature review
publisher	De Gruyter
publishDate	2021
url	https://doaj.org/article/f45c1848c1684d518311004a4441915a
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Perimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism: A case report and literature review

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