Basal condensation of Numb and Pon complex via phase transition during Drosophila neuroblast asymmetric division
Polarized localization of Numb and Pon in Drosophila neuroblasts (NBs) enables their unequal segregation during asymmetric cell divisions. Here, the authors demonstrate liquid-liquid phase separation of Pon and Numb in NBs mediated by multivalent intermolecular interactions is required for their bas...
Enregistré dans:
Auteurs principaux: | Zelin Shan, Yuting Tu, Ying Yang, Ziheng Liu, Menglong Zeng, Huisha Xu, Jiafu Long, Mingjie Zhang, Yu Cai, Wenyu Wen |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/f45e83778d8742c9b81a80ceb914abed |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
The last-born daughter cell contributes to division orientation of Drosophila larval neuroblasts
par: Nicolas Loyer, et autres
Publié: (2018) -
Pain, numbness, or both? Distinguishing the longitudinal course and predictors of positive, painful neuropathic features vs numbness after breast cancer surgery
par: K. Mikayla Flowers, et autres
Publié: (2021) -
Phases of cortical actomyosin dynamics coupled to the neuroblast polarity cycle
par: Chet Huan Oon, et autres
Publié: (2021) -
Par3 cooperates with Sanpodo for the assembly of Notch clusters following asymmetric division of Drosophila sensory organ precursor cells
par: Elise Houssin, et autres
Publié: (2021) -
Construction of intracellular asymmetry and asymmetric division in Escherichia coli
par: Da-Wei Lin, et autres
Publié: (2021)