Maintenance of epigenetic landscape requires CIZ1 and is corrupted in differentiated fibroblasts in long-term culture
The inactive X chromosome (Xi) is a model for establishment and maintenance of repressed chromatin and the function of polycomb repressive complexes. Here the authors show that Xi transiently relocates from the nuclear periphery during replication in a CIZ1-dependent manner, which plays a role in ma...
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Autores principales: | Emma R. Stewart, Robert M. L. Turner, Katherine Newling, Rebeca Ridings-Figueroa, Victoria Scott, Peter D. Ashton, Justin F. X. Ainscough, Dawn Coverley |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/f461e6cb469a41aaaa4bb9b78a0b0508 |
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