Maintenance of epigenetic landscape requires CIZ1 and is corrupted in differentiated fibroblasts in long-term culture

The inactive X chromosome (Xi) is a model for establishment and maintenance of repressed chromatin and the function of polycomb repressive complexes. Here the authors show that Xi transiently relocates from the nuclear periphery during replication in a CIZ1-dependent manner, which plays a role in ma...

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Autores principales: Emma R. Stewart, Robert M. L. Turner, Katherine Newling, Rebeca Ridings-Figueroa, Victoria Scott, Peter D. Ashton, Justin F. X. Ainscough, Dawn Coverley
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/f461e6cb469a41aaaa4bb9b78a0b0508
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