Exploiting metabolic acidosis in solid cancers using a tumor-agnostic pH-activatable nanoprobe for fluorescence-guided surgery

It is well known that the pH of tumor tissue is lower than that of the corresponding normal adjacent tissue. Here, the authors report a clinical trial of a pH activatable nanoparticle for imaging tumours.

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Autores principales:	F. J. Voskuil, P. J. Steinkamp, T. Zhao, B. van der Vegt, M. Koller, J. J. Doff, Y. Jayalakshmi, J. P. Hartung, J. Gao, B. D. Sumer, M. J. H. Witjes, G. M. van Dam, the SHINE study group
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f464a72146f5457993946c6a765cc8dc
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spelling	oai:doaj.org-article:f464a72146f5457993946c6a765cc8dc2021-12-02T18:02:51ZExploiting metabolic acidosis in solid cancers using a tumor-agnostic pH-activatable nanoprobe for fluorescence-guided surgery10.1038/s41467-020-16814-42041-1723https://doaj.org/article/f464a72146f5457993946c6a765cc8dc2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16814-4https://doaj.org/toc/2041-1723It is well known that the pH of tumor tissue is lower than that of the corresponding normal adjacent tissue. Here, the authors report a clinical trial of a pH activatable nanoparticle for imaging tumours.F. J. VoskuilP. J. SteinkampT. ZhaoB. van der VegtM. KollerJ. J. DoffY. JayalakshmiJ. P. HartungJ. GaoB. D. SumerM. J. H. WitjesG. M. van Damthe SHINE study groupNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q F. J. Voskuil P. J. Steinkamp T. Zhao B. van der Vegt M. Koller J. J. Doff Y. Jayalakshmi J. P. Hartung J. Gao B. D. Sumer M. J. H. Witjes G. M. van Dam the SHINE study group Exploiting metabolic acidosis in solid cancers using a tumor-agnostic pH-activatable nanoprobe for fluorescence-guided surgery
description	It is well known that the pH of tumor tissue is lower than that of the corresponding normal adjacent tissue. Here, the authors report a clinical trial of a pH activatable nanoparticle for imaging tumours.
format	article
author	F. J. Voskuil P. J. Steinkamp T. Zhao B. van der Vegt M. Koller J. J. Doff Y. Jayalakshmi J. P. Hartung J. Gao B. D. Sumer M. J. H. Witjes G. M. van Dam the SHINE study group
author_facet	F. J. Voskuil P. J. Steinkamp T. Zhao B. van der Vegt M. Koller J. J. Doff Y. Jayalakshmi J. P. Hartung J. Gao B. D. Sumer M. J. H. Witjes G. M. van Dam the SHINE study group
author_sort	F. J. Voskuil
title	Exploiting metabolic acidosis in solid cancers using a tumor-agnostic pH-activatable nanoprobe for fluorescence-guided surgery
title_short	Exploiting metabolic acidosis in solid cancers using a tumor-agnostic pH-activatable nanoprobe for fluorescence-guided surgery
title_full	Exploiting metabolic acidosis in solid cancers using a tumor-agnostic pH-activatable nanoprobe for fluorescence-guided surgery
title_fullStr	Exploiting metabolic acidosis in solid cancers using a tumor-agnostic pH-activatable nanoprobe for fluorescence-guided surgery
title_full_unstemmed	Exploiting metabolic acidosis in solid cancers using a tumor-agnostic pH-activatable nanoprobe for fluorescence-guided surgery
title_sort	exploiting metabolic acidosis in solid cancers using a tumor-agnostic ph-activatable nanoprobe for fluorescence-guided surgery
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/f464a72146f5457993946c6a765cc8dc
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Exploiting metabolic acidosis in solid cancers using a tumor-agnostic pH-activatable nanoprobe for fluorescence-guided surgery

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