Study on the prostate cancer-targeting mechanism of aptamer-modified nanoparticles and their potential anticancer effect in vivo

Código QR

Study on the prostate cancer-targeting mechanism of aptamer-modified nanoparticles and their potential anticancer effect in vivo

Xin Wu,1,2,* Zongguang Tai,1,* Quangang Zhu,3,* Wei Fan,4 Baoyue Ding,5 Wei Zhang,1,6 Lijuan Zhang,1 Chong Yao,1 Xiaoyu Wang,1 Xueying Ding,2 Qin Li,2 Xiaoyu Li,2 Gaolin Liu,2 Jiyong Liu,1 Shen Gao1 1Department of Pharmaceutics, Changhai Hospital, Second Military Medical University, 2Department of...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Wu X, Tai Z, Zhu Q, Fan W, Ding B, Zhang W, Zhang L, Yao C, Wang X, Ding X, Li Q, Li X, Liu G, Liu J, Gao S
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/f467e5546b59437f92ac6bf86f2a2d8e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Second-generation aptamer-conjugated PSMA-targeted delivery system for prostate cancer therapy
por: Zhu Q, et al.
Publicado: (2011)

Anti-DR5 monoclonal antibody-mediated DTIC-loaded nanoparticles combining chemotherapy and immunotherapy for malignant melanoma: target formulation development and in vitro anticancer activity
por: Ding B, et al.
Publicado: (2011)

Enhancement of anticancer efficacy using modified lipophilic nanoparticle drug encapsulation
por: Lee P, et al.
Publicado: (2012)

Targeted Treatment of Colon Cancer with Aptamer-Guided Albumin Nanoparticles Loaded with Docetaxel
por: Yu Z, et al.
Publicado: (2020)

In vivo SELEX of bone targeting aptamer in prostate cancer bone metastasis model
por: Chen L, et al.
Publicado: (2018)

Cellular uptake mechanism and intracellular fate of hydrophobically modified pullulan nanoparticles
por: Jiang L, et al.
Publicado: (2013)

Elucidating the in vivo fate of nanocrystals using a physiologically based pharmacokinetic model: a case study with the anticancer agent SNX-2112
por: Dong D, et al.
Publicado: (2015)

In vitro and in vivo evaluation of folate receptor-targeting amphiphilic copolymer-modified liposomes loaded with docetaxel
por: Li X, et al.
Publicado: (2011)

Size- and cell type-dependent cellular uptake, cytotoxicity and in vivo distribution of gold nanoparticles
por: Xia Q, et al.
Publicado: (2019)

Therapeutic Efficacy of Carbon Ion Irradiation Enhanced by 11-MUA-Capped Gold Nanoparticles: An in vitro and in vivo Study
por: Zhang P, et al.
Publicado: (2021)

Diagnosis of prostate cancer using anti-PSMA aptamer A10-3.2-oriented lipid nanobubbles
por: Fan X, et al.
Publicado: (2016)

In vivo Targeting of Liver Cancer with Tissue- and Nuclei-Specific Mesoporous Silica Nanoparticle-Based Nanocarriers in mice
por: Ding Z, et al.
Publicado: (2020)

Surface decoration by Spirulina polysaccharide enhances the cellular uptake and anticancer efficacy of selenium nanoparticles
por: Li Y, et al.
Publicado: (2012)

Degradable gene delivery systems based on Pluronics-modified low-molecular-weight polyethylenimine: preparation, characterization, intracellular trafficking, and cellular distribution
por: Ding X, et al.
Publicado: (2012)

Self-assembled nanoparticles based on the c(RGDfk) peptide for the delivery of siRNA targeting the VEGFR2 gene for tumor therapy
por: Liu L, et al.
Publicado: (2014)

Nucleolin-Targeting AS1411 Aptamer-Modified Micelle for the Co-Delivery of Doxorubicin and miR-519c to Improve the Therapeutic Efficacy in Hepatocellular Carcinoma Treatment
por: Liang X, et al.
Publicado: (2021)

Development of Rifapentine-Loaded PLGA-Based Nanoparticles: In vitro Characterisation and in vivo Study in Mice
por: Liang Q, et al.
Publicado: (2020)

Zinc Oxide Nanoparticles Induce Ferroptotic Neuronal Cell Death in vitro and in vivo
por: Qin X, et al.
Publicado: (2020)

Delivery luteolin with folacin-modified nanoparticle for glioma therapy
por: Wu C, et al.
Publicado: (2019)

The antitumor activity of tumor-homing peptide-modified thermosensitive liposomes containing doxorubicin on MCF-7/ADR: in vitro and in vivo
por: Wang C, et al.
Publicado: (2015)

Aptamer-Conjugated Gold Nanoparticles Targeting Epidermal Growth Factor Receptor Variant III for the Treatment of Glioblastoma
por: Peng L, et al.
Publicado: (2020)

Efficacy and mechanism of tanshinone IIA liquid nanoparticles in preventing experimental postoperative peritoneal adhesions in vivo and in vitro
por: Qin F, et al.
Publicado: (2015)

Aptamers as Versatile Ligands for Biomedical and Pharmaceutical Applications
por: Guan B, et al.
Publicado: (2020)

Inducing cell cycle arrest and apoptosis by dimercaptosuccinic acid modified Fe3O4 magnetic nanoparticles combined with nontoxic concentration of bortezomib and gambogic acid in RPMI-8226 cells
por: Zhang W, et al.
Publicado: (2015)

Aptamer-Targeted Calcium Phosphosilicate Nanoparticles for Effective Imaging of Pancreatic and Prostate Cancer
por: Abraham T, et al.
Publicado: (2021)

Preparation and in vitro and in vivo characterization of cyclosporin A-loaded, PEGylated chitosan-modified, lipid-based nanoparticles
por: Zhang L, et al.
Publicado: (2013)

Nanoparticle-modified chitosan-agarose-gelatin scaffold for sustained release of SDF-1 and BMP-2
por: Wang B, et al.
Publicado: (2018)

Synthesis of liver-targeting dual-ligand modified GCGA/5-FU nanoparticles and their characteristics in vitro and in vivo
por: Chen M, et al.
Publicado: (2013)

pH-dependent and cathepsin B activable CaCO3 nanoprobe for targeted in vivo tumor imaging
por: Sun N, et al.
Publicado: (2019)

Targeted Therapy of Colon Cancer by Aptamer-Guided Holliday Junctions Loaded with Doxorubicin
por: Yao F, et al.
Publicado: (2020)

A novel submicron emulsion system loaded with vincristine&ndash;oleic acid ion-pair complex with improved anticancer effect: in vitro and in vivo studies
por: Zhang T, et al.
Publicado: (2013)

Endoglin-Aptamer-Functionalized Liposome-Equipped PD-1-Silenced T Cells Enhance Antitumoral Immunotherapeutic Effects
por: Xie S, et al.
Publicado: (2021)

In vitro and in vivo evaluation of novel NGR-modified liposomes containing brucine
por: Li S, et al.
Publicado: (2017)

Aptamer-Functionalized Dendrimer Delivery of Plasmid-Encoding lncRNA MEG3 Enhances Gene Therapy in Castration-Resistant Prostate Cancer
por: Tai Z, et al.
Publicado: (2020)

PEG-coated and Gd-loaded fluorescent silica nanoparticles for targeted prostate cancer magnetic resonance imaging and fluorescence imaging
por: Jiang W, et al.
Publicado: (2019)

Preparation and Characterization of Fe3O4@MTX Magnetic Nanoparticles for Thermochemotherapy of Primary Central Nervous System Lymphoma in vitro and in vivo
por: Dai X, et al.
Publicado: (2019)

Enhanced in vitro and in vivo therapeutic efficacy of codrug-loaded nanoparticles against liver cancer
por: Li X, et al.
Publicado: (2012)

The synergistic radiosensitizing effect of tirapazamine-conjugated gold nanoparticles on human hepatoma HepG2 cells under X-ray irradiation
por: Liu X, et al.
Publicado: (2016)

Fabrication Of Dual pH/redox-Responsive Lipid-Polymer Hybrid Nanoparticles For Anticancer Drug Delivery And Controlled Release
por: Men W, et al.
Publicado: (2019)

Efficient delivery of ursolic acid by poly(N-vinylpyrrolidone)-block-poly (ε-caprolactone) nanoparticles for inhibiting the growth of hepatocellular carcinoma in vitro and in vivo
por: Zhang H, et al.
Publicado: (2015)