Tobacco use or body mass--do they predict tuberculosis mortality in Mumbai, India? Results from a population-based cohort study.

Tobacco use and under-nutrition are major public health concerns and tuberculosis is a major cause of morbidity and mortality in India. Using a cohort of 148,173 persons (recruited 1991-1997 and followed-up 1997-2003) the joint effects of tobacco use and BMI on tuberculosis mortality was studied. To...

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Autores principales: Mangesh S Pednekar, Matti Hakama, Prakash C Gupta
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Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/f47cf6d816694aa1aa48f2f163e14e17
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spelling oai:doaj.org-article:f47cf6d816694aa1aa48f2f163e14e172021-11-18T07:10:50ZTobacco use or body mass--do they predict tuberculosis mortality in Mumbai, India? Results from a population-based cohort study.1932-620310.1371/journal.pone.0039443https://doaj.org/article/f47cf6d816694aa1aa48f2f163e14e172012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22848354/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203Tobacco use and under-nutrition are major public health concerns and tuberculosis is a major cause of morbidity and mortality in India. Using a cohort of 148,173 persons (recruited 1991-1997 and followed-up 1997-2003) the joint effects of tobacco use and BMI on tuberculosis mortality was studied. Tobacco use in any form and low-BMI had joint effect on tuberculosis mortality and the interaction effect was synergistic in men and antagonistic in women. Self-reported tuberculosis was associated with increased risk of tuberculosis mortality. In contrast, no such association was observed for self-reported diabetes persons. The risk pattern remained unchanged even after excluding tuberculosis deaths occurred within 1(st) two years of follow-up. This study highlights importance of age consideration of individual while excluding early deaths. Around 27% male tuberculosis deaths were attributable to their being underweight and smoker, while 22% male and 37% female deaths were attributable to their being underweight and smokeless tobacco user.Mangesh S PednekarMangesh S PednekarMatti HakamaPrakash C GuptaPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 7, p e39443 (2012)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Mangesh S Pednekar
Mangesh S Pednekar
Matti Hakama
Prakash C Gupta
Tobacco use or body mass--do they predict tuberculosis mortality in Mumbai, India? Results from a population-based cohort study.
description Tobacco use and under-nutrition are major public health concerns and tuberculosis is a major cause of morbidity and mortality in India. Using a cohort of 148,173 persons (recruited 1991-1997 and followed-up 1997-2003) the joint effects of tobacco use and BMI on tuberculosis mortality was studied. Tobacco use in any form and low-BMI had joint effect on tuberculosis mortality and the interaction effect was synergistic in men and antagonistic in women. Self-reported tuberculosis was associated with increased risk of tuberculosis mortality. In contrast, no such association was observed for self-reported diabetes persons. The risk pattern remained unchanged even after excluding tuberculosis deaths occurred within 1(st) two years of follow-up. This study highlights importance of age consideration of individual while excluding early deaths. Around 27% male tuberculosis deaths were attributable to their being underweight and smoker, while 22% male and 37% female deaths were attributable to their being underweight and smokeless tobacco user.
format article
author Mangesh S Pednekar
Mangesh S Pednekar
Matti Hakama
Prakash C Gupta
author_facet Mangesh S Pednekar
Mangesh S Pednekar
Matti Hakama
Prakash C Gupta
author_sort Mangesh S Pednekar
title Tobacco use or body mass--do they predict tuberculosis mortality in Mumbai, India? Results from a population-based cohort study.
title_short Tobacco use or body mass--do they predict tuberculosis mortality in Mumbai, India? Results from a population-based cohort study.
title_full Tobacco use or body mass--do they predict tuberculosis mortality in Mumbai, India? Results from a population-based cohort study.
title_fullStr Tobacco use or body mass--do they predict tuberculosis mortality in Mumbai, India? Results from a population-based cohort study.
title_full_unstemmed Tobacco use or body mass--do they predict tuberculosis mortality in Mumbai, India? Results from a population-based cohort study.
title_sort tobacco use or body mass--do they predict tuberculosis mortality in mumbai, india? results from a population-based cohort study.
publisher Public Library of Science (PLoS)
publishDate 2012
url https://doaj.org/article/f47cf6d816694aa1aa48f2f163e14e17
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AT mangeshspednekar tobaccouseorbodymassdotheypredicttuberculosismortalityinmumbaiindiaresultsfromapopulationbasedcohortstudy
AT mattihakama tobaccouseorbodymassdotheypredicttuberculosismortalityinmumbaiindiaresultsfromapopulationbasedcohortstudy
AT prakashcgupta tobaccouseorbodymassdotheypredicttuberculosismortalityinmumbaiindiaresultsfromapopulationbasedcohortstudy
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