Tobacco use or body mass--do they predict tuberculosis mortality in Mumbai, India? Results from a population-based cohort study.
Tobacco use and under-nutrition are major public health concerns and tuberculosis is a major cause of morbidity and mortality in India. Using a cohort of 148,173 persons (recruited 1991-1997 and followed-up 1997-2003) the joint effects of tobacco use and BMI on tuberculosis mortality was studied. To...
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oai:doaj.org-article:f47cf6d816694aa1aa48f2f163e14e172021-11-18T07:10:50ZTobacco use or body mass--do they predict tuberculosis mortality in Mumbai, India? Results from a population-based cohort study.1932-620310.1371/journal.pone.0039443https://doaj.org/article/f47cf6d816694aa1aa48f2f163e14e172012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22848354/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203Tobacco use and under-nutrition are major public health concerns and tuberculosis is a major cause of morbidity and mortality in India. Using a cohort of 148,173 persons (recruited 1991-1997 and followed-up 1997-2003) the joint effects of tobacco use and BMI on tuberculosis mortality was studied. Tobacco use in any form and low-BMI had joint effect on tuberculosis mortality and the interaction effect was synergistic in men and antagonistic in women. Self-reported tuberculosis was associated with increased risk of tuberculosis mortality. In contrast, no such association was observed for self-reported diabetes persons. The risk pattern remained unchanged even after excluding tuberculosis deaths occurred within 1(st) two years of follow-up. This study highlights importance of age consideration of individual while excluding early deaths. Around 27% male tuberculosis deaths were attributable to their being underweight and smoker, while 22% male and 37% female deaths were attributable to their being underweight and smokeless tobacco user.Mangesh S PednekarMangesh S PednekarMatti HakamaPrakash C GuptaPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 7, p e39443 (2012) |
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Medicine R Science Q Mangesh S Pednekar Mangesh S Pednekar Matti Hakama Prakash C Gupta Tobacco use or body mass--do they predict tuberculosis mortality in Mumbai, India? Results from a population-based cohort study. |
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Tobacco use and under-nutrition are major public health concerns and tuberculosis is a major cause of morbidity and mortality in India. Using a cohort of 148,173 persons (recruited 1991-1997 and followed-up 1997-2003) the joint effects of tobacco use and BMI on tuberculosis mortality was studied. Tobacco use in any form and low-BMI had joint effect on tuberculosis mortality and the interaction effect was synergistic in men and antagonistic in women. Self-reported tuberculosis was associated with increased risk of tuberculosis mortality. In contrast, no such association was observed for self-reported diabetes persons. The risk pattern remained unchanged even after excluding tuberculosis deaths occurred within 1(st) two years of follow-up. This study highlights importance of age consideration of individual while excluding early deaths. Around 27% male tuberculosis deaths were attributable to their being underweight and smoker, while 22% male and 37% female deaths were attributable to their being underweight and smokeless tobacco user. |
format |
article |
author |
Mangesh S Pednekar Mangesh S Pednekar Matti Hakama Prakash C Gupta |
author_facet |
Mangesh S Pednekar Mangesh S Pednekar Matti Hakama Prakash C Gupta |
author_sort |
Mangesh S Pednekar |
title |
Tobacco use or body mass--do they predict tuberculosis mortality in Mumbai, India? Results from a population-based cohort study. |
title_short |
Tobacco use or body mass--do they predict tuberculosis mortality in Mumbai, India? Results from a population-based cohort study. |
title_full |
Tobacco use or body mass--do they predict tuberculosis mortality in Mumbai, India? Results from a population-based cohort study. |
title_fullStr |
Tobacco use or body mass--do they predict tuberculosis mortality in Mumbai, India? Results from a population-based cohort study. |
title_full_unstemmed |
Tobacco use or body mass--do they predict tuberculosis mortality in Mumbai, India? Results from a population-based cohort study. |
title_sort |
tobacco use or body mass--do they predict tuberculosis mortality in mumbai, india? results from a population-based cohort study. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2012 |
url |
https://doaj.org/article/f47cf6d816694aa1aa48f2f163e14e17 |
work_keys_str_mv |
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