Reporters transiently transfected into mammalian cells are highly sensitive to translational repression induced by dsRNA expression.
In mammals, double-stranded RNA (dsRNA) can mediate sequence-specific RNA interference, activate sequence-independent interferon response, or undergo RNA editing by adenosine deaminases. We showed that long hairpin dsRNA expression had negligible effects on mammalian somatic cells--expressed dsRNA w...
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| Auteurs principaux: | , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2014
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| Accès en ligne: | https://doaj.org/article/f4804606d4fb43caa33a3f785c5e8e0e |
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