Prediction of allosteric sites and mediating interactions through bond-to-bond propensities

Allostery is a key molecular mechanism underpinning control and modulation in a variety of cellular processes. Here, the authors present a method that can be used to predict allosteric sites and the mediating interactions that connect them to the active site of the protein.

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Detalles Bibliográficos
Autores principales: B. R. C. Amor, M. T. Schaub, S. N. Yaliraki, M. Barahona
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
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Acceso en línea:https://doaj.org/article/f484ae3ccedb45429a2495eabb804566
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Descripción
Sumario:Allostery is a key molecular mechanism underpinning control and modulation in a variety of cellular processes. Here, the authors present a method that can be used to predict allosteric sites and the mediating interactions that connect them to the active site of the protein.