Prediction of allosteric sites and mediating interactions through bond-to-bond propensities

Allostery is a key molecular mechanism underpinning control and modulation in a variety of cellular processes. Here, the authors present a method that can be used to predict allosteric sites and the mediating interactions that connect them to the active site of the protein.

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Autores principales: B. R. C. Amor, M. T. Schaub, S. N. Yaliraki, M. Barahona
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/f484ae3ccedb45429a2495eabb804566
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spelling oai:doaj.org-article:f484ae3ccedb45429a2495eabb8045662021-12-02T15:35:25ZPrediction of allosteric sites and mediating interactions through bond-to-bond propensities10.1038/ncomms124772041-1723https://doaj.org/article/f484ae3ccedb45429a2495eabb8045662016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12477https://doaj.org/toc/2041-1723Allostery is a key molecular mechanism underpinning control and modulation in a variety of cellular processes. Here, the authors present a method that can be used to predict allosteric sites and the mediating interactions that connect them to the active site of the protein.B. R. C. AmorM. T. SchaubS. N. YalirakiM. BarahonaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
B. R. C. Amor
M. T. Schaub
S. N. Yaliraki
M. Barahona
Prediction of allosteric sites and mediating interactions through bond-to-bond propensities
description Allostery is a key molecular mechanism underpinning control and modulation in a variety of cellular processes. Here, the authors present a method that can be used to predict allosteric sites and the mediating interactions that connect them to the active site of the protein.
format article
author B. R. C. Amor
M. T. Schaub
S. N. Yaliraki
M. Barahona
author_facet B. R. C. Amor
M. T. Schaub
S. N. Yaliraki
M. Barahona
author_sort B. R. C. Amor
title Prediction of allosteric sites and mediating interactions through bond-to-bond propensities
title_short Prediction of allosteric sites and mediating interactions through bond-to-bond propensities
title_full Prediction of allosteric sites and mediating interactions through bond-to-bond propensities
title_fullStr Prediction of allosteric sites and mediating interactions through bond-to-bond propensities
title_full_unstemmed Prediction of allosteric sites and mediating interactions through bond-to-bond propensities
title_sort prediction of allosteric sites and mediating interactions through bond-to-bond propensities
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/f484ae3ccedb45429a2495eabb804566
work_keys_str_mv AT brcamor predictionofallostericsitesandmediatinginteractionsthroughbondtobondpropensities
AT mtschaub predictionofallostericsitesandmediatinginteractionsthroughbondtobondpropensities
AT snyaliraki predictionofallostericsitesandmediatinginteractionsthroughbondtobondpropensities
AT mbarahona predictionofallostericsitesandmediatinginteractionsthroughbondtobondpropensities
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