Prediction of allosteric sites and mediating interactions through bond-to-bond propensities
Allostery is a key molecular mechanism underpinning control and modulation in a variety of cellular processes. Here, the authors present a method that can be used to predict allosteric sites and the mediating interactions that connect them to the active site of the protein.
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Nature Portfolio
2016
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oai:doaj.org-article:f484ae3ccedb45429a2495eabb8045662021-12-02T15:35:25ZPrediction of allosteric sites and mediating interactions through bond-to-bond propensities10.1038/ncomms124772041-1723https://doaj.org/article/f484ae3ccedb45429a2495eabb8045662016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12477https://doaj.org/toc/2041-1723Allostery is a key molecular mechanism underpinning control and modulation in a variety of cellular processes. Here, the authors present a method that can be used to predict allosteric sites and the mediating interactions that connect them to the active site of the protein.B. R. C. AmorM. T. SchaubS. N. YalirakiM. BarahonaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016) |
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Science Q B. R. C. Amor M. T. Schaub S. N. Yaliraki M. Barahona Prediction of allosteric sites and mediating interactions through bond-to-bond propensities |
description |
Allostery is a key molecular mechanism underpinning control and modulation in a variety of cellular processes. Here, the authors present a method that can be used to predict allosteric sites and the mediating interactions that connect them to the active site of the protein. |
format |
article |
author |
B. R. C. Amor M. T. Schaub S. N. Yaliraki M. Barahona |
author_facet |
B. R. C. Amor M. T. Schaub S. N. Yaliraki M. Barahona |
author_sort |
B. R. C. Amor |
title |
Prediction of allosteric sites and mediating interactions through bond-to-bond propensities |
title_short |
Prediction of allosteric sites and mediating interactions through bond-to-bond propensities |
title_full |
Prediction of allosteric sites and mediating interactions through bond-to-bond propensities |
title_fullStr |
Prediction of allosteric sites and mediating interactions through bond-to-bond propensities |
title_full_unstemmed |
Prediction of allosteric sites and mediating interactions through bond-to-bond propensities |
title_sort |
prediction of allosteric sites and mediating interactions through bond-to-bond propensities |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/f484ae3ccedb45429a2495eabb804566 |
work_keys_str_mv |
AT brcamor predictionofallostericsitesandmediatinginteractionsthroughbondtobondpropensities AT mtschaub predictionofallostericsitesandmediatinginteractionsthroughbondtobondpropensities AT snyaliraki predictionofallostericsitesandmediatinginteractionsthroughbondtobondpropensities AT mbarahona predictionofallostericsitesandmediatinginteractionsthroughbondtobondpropensities |
_version_ |
1718386570699997184 |