Survival of an elderly patient with lung cancer treated with first-line chemotherapy

Introduction: Lung cancer is taking an increasing toll on the older population as life expectancy increases. However, the efficacy of chemotherapy is difficult to establish and the prognosis of these patients is severe. Objective: Report a case of an older adult patient with advanced non-small cell...

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Autores principales:	Oscar Augusto Quintana Blancos, Rita Emily Vallejos Garcia, Rodolfo Cristóbal Olmos Soldevilla, José Fernando Salvador Carrillo, José Luis Salinas Paz
Formato:	article
Lenguaje:	ES
Publicado:	ECIMED 2021
Materias:	sobrevida adenocarcinoma cáncer de pulmón de células no pequeñas avanzado adulto mayor quimioterapia. Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/f4a34929c0b74dc6b783c518b769a8e1
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spelling	oai:doaj.org-article:f4a34929c0b74dc6b783c518b769a8e12021-12-03T13:28:50ZSurvival of an elderly patient with lung cancer treated with first-line chemotherapy1561-3046https://doaj.org/article/f4a34929c0b74dc6b783c518b769a8e12021-10-01T00:00:00Zhttp://revmedmilitar.sld.cu/index.php/mil/article/view/1154https://doaj.org/toc/1561-3046Introduction: Lung cancer is taking an increasing toll on the older population as life expectancy increases. However, the efficacy of chemotherapy is difficult to establish and the prognosis of these patients is severe. Objective: Report a case of an older adult patient with advanced non-small cell lung cancer with prolonged survival who received only first-line chemotherapy. Case report: A 71-year-old non-smoker patient diagnosed with advanced non-small cell lung cancer, adenocarcinoma subtype, with pleural involvement. He started treatment with carboplatin 5 AUC and gemcitabine 1,1 g. In the ninth cycle, reduction of pulmonary nodules was found, but he also had metastases at the D6-D7 level. He started the second line of treatment with carboplatin 5,4 AUC, paclitaxel 200 mg and zolendronic acid at a dose of 4,0 mg. Due to adverse events, the treatment was changed to vinorelbine 2,5 g and zolendronic acid 4.0 mg. After two cycles, the patient died, reaching 21 months of overall survival, only with chemotherapy. Conclusion: The treatment of the older adult patient with lung cancer is challenging. In the present chemotherapy treatment, the patient was able to achieve 21 months of overall survival, despite the fact that he was not molecularly characterized.Oscar Augusto Quintana BlancosRita Emily Vallejos GarciaRodolfo Cristóbal Olmos SoldevillaJosé Fernando Salvador CarrilloJosé Luis Salinas PazECIMEDarticlesobrevidaadenocarcinomacáncer de pulmón de células no pequeñas avanzadoadulto mayorquimioterapia.MedicineRMedicine (General)R5-920ESRevista Cubana de Medicina Militar, Vol 50, Iss 4, Pp e02101154-e02101154 (2021)
institution	DOAJ
collection	DOAJ
language	ES
topic	sobrevida adenocarcinoma cáncer de pulmón de células no pequeñas avanzado adulto mayor quimioterapia. Medicine R Medicine (General) R5-920
spellingShingle	sobrevida adenocarcinoma cáncer de pulmón de células no pequeñas avanzado adulto mayor quimioterapia. Medicine R Medicine (General) R5-920 Oscar Augusto Quintana Blancos Rita Emily Vallejos Garcia Rodolfo Cristóbal Olmos Soldevilla José Fernando Salvador Carrillo José Luis Salinas Paz Survival of an elderly patient with lung cancer treated with first-line chemotherapy
description	Introduction: Lung cancer is taking an increasing toll on the older population as life expectancy increases. However, the efficacy of chemotherapy is difficult to establish and the prognosis of these patients is severe. Objective: Report a case of an older adult patient with advanced non-small cell lung cancer with prolonged survival who received only first-line chemotherapy. Case report: A 71-year-old non-smoker patient diagnosed with advanced non-small cell lung cancer, adenocarcinoma subtype, with pleural involvement. He started treatment with carboplatin 5 AUC and gemcitabine 1,1 g. In the ninth cycle, reduction of pulmonary nodules was found, but he also had metastases at the D6-D7 level. He started the second line of treatment with carboplatin 5,4 AUC, paclitaxel 200 mg and zolendronic acid at a dose of 4,0 mg. Due to adverse events, the treatment was changed to vinorelbine 2,5 g and zolendronic acid 4.0 mg. After two cycles, the patient died, reaching 21 months of overall survival, only with chemotherapy. Conclusion: The treatment of the older adult patient with lung cancer is challenging. In the present chemotherapy treatment, the patient was able to achieve 21 months of overall survival, despite the fact that he was not molecularly characterized.
format	article
author	Oscar Augusto Quintana Blancos Rita Emily Vallejos Garcia Rodolfo Cristóbal Olmos Soldevilla José Fernando Salvador Carrillo José Luis Salinas Paz
author_facet	Oscar Augusto Quintana Blancos Rita Emily Vallejos Garcia Rodolfo Cristóbal Olmos Soldevilla José Fernando Salvador Carrillo José Luis Salinas Paz
author_sort	Oscar Augusto Quintana Blancos
title	Survival of an elderly patient with lung cancer treated with first-line chemotherapy
title_short	Survival of an elderly patient with lung cancer treated with first-line chemotherapy
title_full	Survival of an elderly patient with lung cancer treated with first-line chemotherapy
title_fullStr	Survival of an elderly patient with lung cancer treated with first-line chemotherapy
title_full_unstemmed	Survival of an elderly patient with lung cancer treated with first-line chemotherapy
title_sort	survival of an elderly patient with lung cancer treated with first-line chemotherapy
publisher	ECIMED
publishDate	2021
url	https://doaj.org/article/f4a34929c0b74dc6b783c518b769a8e1
work_keys_str_mv	AT oscaraugustoquintanablancos survivalofanelderlypatientwithlungcancertreatedwithfirstlinechemotherapy AT ritaemilyvallejosgarcia survivalofanelderlypatientwithlungcancertreatedwithfirstlinechemotherapy AT rodolfocristobalolmossoldevilla survivalofanelderlypatientwithlungcancertreatedwithfirstlinechemotherapy AT josefernandosalvadorcarrillo survivalofanelderlypatientwithlungcancertreatedwithfirstlinechemotherapy AT joseluissalinaspaz survivalofanelderlypatientwithlungcancertreatedwithfirstlinechemotherapy
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Survival of an elderly patient with lung cancer treated with first-line chemotherapy

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