Changes in the diurnal rhythms during a 45-day head-down bed rest.
In spaceflight human circadian rhythms and sleep patterns are likely subject to change, which consequently disturbs human physiology, cognitive abilities and performance efficiency. However, the influence of microgravity on sleep and circadian clock as well as the underlying mechanisms remain largel...
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Public Library of Science (PLoS)
2012
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/f4a3dfd711db4996bfb75f6129c66977 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:f4a3dfd711db4996bfb75f6129c66977 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:f4a3dfd711db4996bfb75f6129c669772021-11-18T08:11:18ZChanges in the diurnal rhythms during a 45-day head-down bed rest.1932-620310.1371/journal.pone.0047984https://doaj.org/article/f4a3dfd711db4996bfb75f6129c669772012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23110150/?tool=EBIhttps://doaj.org/toc/1932-6203In spaceflight human circadian rhythms and sleep patterns are likely subject to change, which consequently disturbs human physiology, cognitive abilities and performance efficiency. However, the influence of microgravity on sleep and circadian clock as well as the underlying mechanisms remain largely unknown. Placing volunteers in a prone position, whereby their heads rest at an angle of -6° below horizontal, mimics the microgravity environment in orbital flight. Such positioning is termed head-down bed rest (HDBR). In this work, we analysed the influence of a 45-day HDBR on physiological diurnal rhythms. We examined urinary electrolyte and hormone excretion, and the results show a dramatic elevation of cortisol levels during HDBR and recovery. Increased diuresis, melatonin and testosterone were observed at certain periods during HDBR. In addition, we investigated the changes in urination and defecation frequencies and found that the rhythmicity of urinary frequency during lights-off during and after HDBR was higher than control. The grouped defecation frequency data exhibits rhythmicity before and during HDBR but not after HDBR. Together, these data demonstrate that HDBR can alter a number of physiological processes associated with diurnal rhythms.Xiaodi LiangLin ZhangYufeng WanXinyang YuYiming GuoXiaoping ChenCheng TanTianle HuangHanjie ShenXianyun ChenHongying LiKe LvFei SunShanguang ChenJinhu GuoPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 10, p e47984 (2012) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Medicine R Science Q |
| spellingShingle |
Medicine R Science Q Xiaodi Liang Lin Zhang Yufeng Wan Xinyang Yu Yiming Guo Xiaoping Chen Cheng Tan Tianle Huang Hanjie Shen Xianyun Chen Hongying Li Ke Lv Fei Sun Shanguang Chen Jinhu Guo Changes in the diurnal rhythms during a 45-day head-down bed rest. |
| description |
In spaceflight human circadian rhythms and sleep patterns are likely subject to change, which consequently disturbs human physiology, cognitive abilities and performance efficiency. However, the influence of microgravity on sleep and circadian clock as well as the underlying mechanisms remain largely unknown. Placing volunteers in a prone position, whereby their heads rest at an angle of -6° below horizontal, mimics the microgravity environment in orbital flight. Such positioning is termed head-down bed rest (HDBR). In this work, we analysed the influence of a 45-day HDBR on physiological diurnal rhythms. We examined urinary electrolyte and hormone excretion, and the results show a dramatic elevation of cortisol levels during HDBR and recovery. Increased diuresis, melatonin and testosterone were observed at certain periods during HDBR. In addition, we investigated the changes in urination and defecation frequencies and found that the rhythmicity of urinary frequency during lights-off during and after HDBR was higher than control. The grouped defecation frequency data exhibits rhythmicity before and during HDBR but not after HDBR. Together, these data demonstrate that HDBR can alter a number of physiological processes associated with diurnal rhythms. |
| format |
article |
| author |
Xiaodi Liang Lin Zhang Yufeng Wan Xinyang Yu Yiming Guo Xiaoping Chen Cheng Tan Tianle Huang Hanjie Shen Xianyun Chen Hongying Li Ke Lv Fei Sun Shanguang Chen Jinhu Guo |
| author_facet |
Xiaodi Liang Lin Zhang Yufeng Wan Xinyang Yu Yiming Guo Xiaoping Chen Cheng Tan Tianle Huang Hanjie Shen Xianyun Chen Hongying Li Ke Lv Fei Sun Shanguang Chen Jinhu Guo |
| author_sort |
Xiaodi Liang |
| title |
Changes in the diurnal rhythms during a 45-day head-down bed rest. |
| title_short |
Changes in the diurnal rhythms during a 45-day head-down bed rest. |
| title_full |
Changes in the diurnal rhythms during a 45-day head-down bed rest. |
| title_fullStr |
Changes in the diurnal rhythms during a 45-day head-down bed rest. |
| title_full_unstemmed |
Changes in the diurnal rhythms during a 45-day head-down bed rest. |
| title_sort |
changes in the diurnal rhythms during a 45-day head-down bed rest. |
| publisher |
Public Library of Science (PLoS) |
| publishDate |
2012 |
| url |
https://doaj.org/article/f4a3dfd711db4996bfb75f6129c66977 |
| work_keys_str_mv |
AT xiaodiliang changesinthediurnalrhythmsduringa45dayheaddownbedrest AT linzhang changesinthediurnalrhythmsduringa45dayheaddownbedrest AT yufengwan changesinthediurnalrhythmsduringa45dayheaddownbedrest AT xinyangyu changesinthediurnalrhythmsduringa45dayheaddownbedrest AT yimingguo changesinthediurnalrhythmsduringa45dayheaddownbedrest AT xiaopingchen changesinthediurnalrhythmsduringa45dayheaddownbedrest AT chengtan changesinthediurnalrhythmsduringa45dayheaddownbedrest AT tianlehuang changesinthediurnalrhythmsduringa45dayheaddownbedrest AT hanjieshen changesinthediurnalrhythmsduringa45dayheaddownbedrest AT xianyunchen changesinthediurnalrhythmsduringa45dayheaddownbedrest AT hongyingli changesinthediurnalrhythmsduringa45dayheaddownbedrest AT kelv changesinthediurnalrhythmsduringa45dayheaddownbedrest AT feisun changesinthediurnalrhythmsduringa45dayheaddownbedrest AT shanguangchen changesinthediurnalrhythmsduringa45dayheaddownbedrest AT jinhuguo changesinthediurnalrhythmsduringa45dayheaddownbedrest |
| _version_ |
1718422145002897408 |