TBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex

TBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex

The T-box protein TBR2 is involved in cortical neurogenesis expansion during neurodevelopment and is preferentially enriched in intermediate progenitors. The authors show that TBR2 coordinates neurogenesis expansion and precise microcircuit assembly in the mouse cortex via PCDH19.

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Bibliographic Details
Main Authors: Xiaohui Lv, Si-Qiang Ren, Xin-Jun Zhang, Zhongfu Shen, Tanay Ghosh, Anjin Xianyu, Peng Gao, Zhizhong Li, Susan Lin, Yang Yu, Qiangqiang Zhang, Matthias Groszer, Song-Hai Shi
Format: article
Language:EN
Published: Nature Portfolio 2019
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Science
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Online Access:https://doaj.org/article/f4a5d9c9f50f44238de1e4075548dbfd
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Summary:The T-box protein TBR2 is involved in cortical neurogenesis expansion during neurodevelopment and is preferentially enriched in intermediate progenitors. The authors show that TBR2 coordinates neurogenesis expansion and precise microcircuit assembly in the mouse cortex via PCDH19.

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