TBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex

The T-box protein TBR2 is involved in cortical neurogenesis expansion during neurodevelopment and is preferentially enriched in intermediate progenitors. The authors show that TBR2 coordinates neurogenesis expansion and precise microcircuit assembly in the mouse cortex via PCDH19.

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Autores principales: Xiaohui Lv, Si-Qiang Ren, Xin-Jun Zhang, Zhongfu Shen, Tanay Ghosh, Anjin Xianyu, Peng Gao, Zhizhong Li, Susan Lin, Yang Yu, Qiangqiang Zhang, Matthias Groszer, Song-Hai Shi
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/f4a5d9c9f50f44238de1e4075548dbfd
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spelling oai:doaj.org-article:f4a5d9c9f50f44238de1e4075548dbfd2021-12-02T16:58:29ZTBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex10.1038/s41467-019-11854-x2041-1723https://doaj.org/article/f4a5d9c9f50f44238de1e4075548dbfd2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11854-xhttps://doaj.org/toc/2041-1723The T-box protein TBR2 is involved in cortical neurogenesis expansion during neurodevelopment and is preferentially enriched in intermediate progenitors. The authors show that TBR2 coordinates neurogenesis expansion and precise microcircuit assembly in the mouse cortex via PCDH19.Xiaohui LvSi-Qiang RenXin-Jun ZhangZhongfu ShenTanay GhoshAnjin XianyuPeng GaoZhizhong LiSusan LinYang YuQiangqiang ZhangMatthias GroszerSong-Hai ShiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xiaohui Lv
Si-Qiang Ren
Xin-Jun Zhang
Zhongfu Shen
Tanay Ghosh
Anjin Xianyu
Peng Gao
Zhizhong Li
Susan Lin
Yang Yu
Qiangqiang Zhang
Matthias Groszer
Song-Hai Shi
TBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex
description The T-box protein TBR2 is involved in cortical neurogenesis expansion during neurodevelopment and is preferentially enriched in intermediate progenitors. The authors show that TBR2 coordinates neurogenesis expansion and precise microcircuit assembly in the mouse cortex via PCDH19.
format article
author Xiaohui Lv
Si-Qiang Ren
Xin-Jun Zhang
Zhongfu Shen
Tanay Ghosh
Anjin Xianyu
Peng Gao
Zhizhong Li
Susan Lin
Yang Yu
Qiangqiang Zhang
Matthias Groszer
Song-Hai Shi
author_facet Xiaohui Lv
Si-Qiang Ren
Xin-Jun Zhang
Zhongfu Shen
Tanay Ghosh
Anjin Xianyu
Peng Gao
Zhizhong Li
Susan Lin
Yang Yu
Qiangqiang Zhang
Matthias Groszer
Song-Hai Shi
author_sort Xiaohui Lv
title TBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex
title_short TBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex
title_full TBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex
title_fullStr TBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex
title_full_unstemmed TBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex
title_sort tbr2 coordinates neurogenesis expansion and precise microcircuit organization via protocadherin 19 in the mammalian cortex
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/f4a5d9c9f50f44238de1e4075548dbfd
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