Association between inter-leg blood pressure difference and cardiovascular outcome in patients undergoing percutaneous coronary intervention.

<h4>Background</h4>Although the inter-arm blood pressure (BP) difference has been advocated to be associated with cardiovascular events, the implication of inter-leg BP difference has not been well established. This study was conducted to investigate whether inter-arm and -leg BP differe...

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Autores principales:	Inki Moon, Hack-Lyoung Kim, Woo-Hyun Lim, Jae-Bin Seo, Joo-Hee Zo, Myung-A Kim, Sang-Hyun Kim
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/f4a6e9a1db3e488bbc9bb3ece6f956c1
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spelling	oai:doaj.org-article:f4a6e9a1db3e488bbc9bb3ece6f956c12021-12-02T20:16:52ZAssociation between inter-leg blood pressure difference and cardiovascular outcome in patients undergoing percutaneous coronary intervention.1932-620310.1371/journal.pone.0257443https://doaj.org/article/f4a6e9a1db3e488bbc9bb3ece6f956c12021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0257443https://doaj.org/toc/1932-6203<h4>Background</h4>Although the inter-arm blood pressure (BP) difference has been advocated to be associated with cardiovascular events, the implication of inter-leg BP difference has not been well established. This study was conducted to investigate whether inter-arm and -leg BP differences have prognostic value in patients undergoing percutaneous coronary intervention (PCI).<h4>Methods</h4>In this prospective study, we consecutively enrolled 667 patients who underwent PCI. Both arm and leg BPs were measured at the day after PCI. The primary outcome was a major adverse cardiovascular event (MACE) including cardiac death, acute coronary syndrome, coronary revascularization, stroke, and hospitalization for heart failure during the follow-up period.<h4>Results</h4>Mean age was 64.0±11.1 years old, and males were predominant (70.5%). During a mean follow-up period of 3.0 years, MACE occurred in 209 (31.3%) patients. The inter-leg systolic BP difference (ILSBPD) was significantly higher in patients with MACE than those without (9.9±12.3 vs. 7.2±7.5 mmHg, P = 0.004). The inter-arm systolic BP difference was not significantly different between patients with and without MACE (P = 0.403). In multivariable Cox regression analysis, increased ILSBPD was independently associated with the development of MACE (per 5 mmHg; hazard ratio, 1.07; 95% confidence interval, 1.01-1.14). The inter-arm systolic BP difference was not associated with MACE in the multivariable analysis.<h4>Conclusion</h4>Increased ILSBPD was independently associated with worse cardiovascular outcomes after PCI. As ILSBPD is easy to measure, it may be helpful in the risk stratification of patients undergoing PCI.Inki MoonHack-Lyoung KimWoo-Hyun LimJae-Bin SeoJoo-Hee ZoMyung-A KimSang-Hyun KimPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 10, p e0257443 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Inki Moon Hack-Lyoung Kim Woo-Hyun Lim Jae-Bin Seo Joo-Hee Zo Myung-A Kim Sang-Hyun Kim Association between inter-leg blood pressure difference and cardiovascular outcome in patients undergoing percutaneous coronary intervention.
description	<h4>Background</h4>Although the inter-arm blood pressure (BP) difference has been advocated to be associated with cardiovascular events, the implication of inter-leg BP difference has not been well established. This study was conducted to investigate whether inter-arm and -leg BP differences have prognostic value in patients undergoing percutaneous coronary intervention (PCI).<h4>Methods</h4>In this prospective study, we consecutively enrolled 667 patients who underwent PCI. Both arm and leg BPs were measured at the day after PCI. The primary outcome was a major adverse cardiovascular event (MACE) including cardiac death, acute coronary syndrome, coronary revascularization, stroke, and hospitalization for heart failure during the follow-up period.<h4>Results</h4>Mean age was 64.0±11.1 years old, and males were predominant (70.5%). During a mean follow-up period of 3.0 years, MACE occurred in 209 (31.3%) patients. The inter-leg systolic BP difference (ILSBPD) was significantly higher in patients with MACE than those without (9.9±12.3 vs. 7.2±7.5 mmHg, P = 0.004). The inter-arm systolic BP difference was not significantly different between patients with and without MACE (P = 0.403). In multivariable Cox regression analysis, increased ILSBPD was independently associated with the development of MACE (per 5 mmHg; hazard ratio, 1.07; 95% confidence interval, 1.01-1.14). The inter-arm systolic BP difference was not associated with MACE in the multivariable analysis.<h4>Conclusion</h4>Increased ILSBPD was independently associated with worse cardiovascular outcomes after PCI. As ILSBPD is easy to measure, it may be helpful in the risk stratification of patients undergoing PCI.
format	article
author	Inki Moon Hack-Lyoung Kim Woo-Hyun Lim Jae-Bin Seo Joo-Hee Zo Myung-A Kim Sang-Hyun Kim
author_facet	Inki Moon Hack-Lyoung Kim Woo-Hyun Lim Jae-Bin Seo Joo-Hee Zo Myung-A Kim Sang-Hyun Kim
author_sort	Inki Moon
title	Association between inter-leg blood pressure difference and cardiovascular outcome in patients undergoing percutaneous coronary intervention.
title_short	Association between inter-leg blood pressure difference and cardiovascular outcome in patients undergoing percutaneous coronary intervention.
title_full	Association between inter-leg blood pressure difference and cardiovascular outcome in patients undergoing percutaneous coronary intervention.
title_fullStr	Association between inter-leg blood pressure difference and cardiovascular outcome in patients undergoing percutaneous coronary intervention.
title_full_unstemmed	Association between inter-leg blood pressure difference and cardiovascular outcome in patients undergoing percutaneous coronary intervention.
title_sort	association between inter-leg blood pressure difference and cardiovascular outcome in patients undergoing percutaneous coronary intervention.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/f4a6e9a1db3e488bbc9bb3ece6f956c1
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Association between inter-leg blood pressure difference and cardiovascular outcome in patients undergoing percutaneous coronary intervention.

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