High-throughput cell and spheroid mechanics in virtual fluidic channels

High-throughput rheological measurements of cells and cell clusters by microfluidics is limited by fixed channel dimensions. Here the authors create virtual fluidic channels inside the cuvette of commercial flow cytometers to dynamically tune channel cross section to enable rheological measurements...

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Autores principales: Muzaffar H. Panhwar, Fabian Czerwinski, Venkata A. S. Dabbiru, Yesaswini Komaragiri, Bob Fregin, Doreen Biedenweg, Peter Nestler, Ricardo H. Pires, Oliver Otto
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/f4a8266538d44b5b8fc29419418838fe
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spelling oai:doaj.org-article:f4a8266538d44b5b8fc29419418838fe2021-12-02T14:42:30ZHigh-throughput cell and spheroid mechanics in virtual fluidic channels10.1038/s41467-020-15813-92041-1723https://doaj.org/article/f4a8266538d44b5b8fc29419418838fe2020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15813-9https://doaj.org/toc/2041-1723High-throughput rheological measurements of cells and cell clusters by microfluidics is limited by fixed channel dimensions. Here the authors create virtual fluidic channels inside the cuvette of commercial flow cytometers to dynamically tune channel cross section to enable rheological measurements from cells and cell clusters.Muzaffar H. PanhwarFabian CzerwinskiVenkata A. S. DabbiruYesaswini KomaragiriBob FreginDoreen BiedenwegPeter NestlerRicardo H. PiresOliver OttoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Muzaffar H. Panhwar
Fabian Czerwinski
Venkata A. S. Dabbiru
Yesaswini Komaragiri
Bob Fregin
Doreen Biedenweg
Peter Nestler
Ricardo H. Pires
Oliver Otto
High-throughput cell and spheroid mechanics in virtual fluidic channels
description High-throughput rheological measurements of cells and cell clusters by microfluidics is limited by fixed channel dimensions. Here the authors create virtual fluidic channels inside the cuvette of commercial flow cytometers to dynamically tune channel cross section to enable rheological measurements from cells and cell clusters.
format article
author Muzaffar H. Panhwar
Fabian Czerwinski
Venkata A. S. Dabbiru
Yesaswini Komaragiri
Bob Fregin
Doreen Biedenweg
Peter Nestler
Ricardo H. Pires
Oliver Otto
author_facet Muzaffar H. Panhwar
Fabian Czerwinski
Venkata A. S. Dabbiru
Yesaswini Komaragiri
Bob Fregin
Doreen Biedenweg
Peter Nestler
Ricardo H. Pires
Oliver Otto
author_sort Muzaffar H. Panhwar
title High-throughput cell and spheroid mechanics in virtual fluidic channels
title_short High-throughput cell and spheroid mechanics in virtual fluidic channels
title_full High-throughput cell and spheroid mechanics in virtual fluidic channels
title_fullStr High-throughput cell and spheroid mechanics in virtual fluidic channels
title_full_unstemmed High-throughput cell and spheroid mechanics in virtual fluidic channels
title_sort high-throughput cell and spheroid mechanics in virtual fluidic channels
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/f4a8266538d44b5b8fc29419418838fe
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