DNA binding strength increases the processivity and activity of a Y-Family DNA polymerase
Abstract DNA polymerase (pol) processivity, i.e., the bases a polymerase extends before falling off the DNA, and activity are important for copying difficult DNA sequences, including simple repeats. Y-family pols would be appealing for copying difficult DNA and incorporating non-natural dNTPs, due t...
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Autores principales: | Jing Wu, Alexandra de Paz, Bradley M. Zamft, Adam H. Marblestone, Edward S. Boyden, Konrad P. Kording, Keith E. J. Tyo |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/f4b1ec7d932b45bca5803a0278a5f0b6 |
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