Host CDK-1 and formin mediate microvillar effacement induced by enterohemorrhagic Escherichia coli

Enterohemorrhagic Escherichia coli (EHEC) induces formation of attaching and effacing lesions in the intestine. Here, Huang et al. use human intestinal cells and a C. elegans model of infection to show that the process is mediated by a host signaling pathway involving cyclin-dependent kinase CDK1 an...

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Autores principales:	Cheng-Rung Huang, Cheng-Ju Kuo, Chih-Wen Huang, Yu-Ting Chen, Bang-Yu Liu, Chung-Ta Lee, Po-Lin Chen, Wen-Tsan Chang, Yun-Wen Chen, Tzer-Min Lee, Hui-Chen Hsieh, Chang-Shi Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f4b63533b7a9482ab5bd4e6b416ad6a9
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:f4b63533b7a9482ab5bd4e6b416ad6a92021-12-02T11:56:18ZHost CDK-1 and formin mediate microvillar effacement induced by enterohemorrhagic Escherichia coli10.1038/s41467-020-20355-12041-1723https://doaj.org/article/f4b63533b7a9482ab5bd4e6b416ad6a92021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20355-1https://doaj.org/toc/2041-1723Enterohemorrhagic Escherichia coli (EHEC) induces formation of attaching and effacing lesions in the intestine. Here, Huang et al. use human intestinal cells and a C. elegans model of infection to show that the process is mediated by a host signaling pathway involving cyclin-dependent kinase CDK1 and formin CYK1.Cheng-Rung HuangCheng-Ju KuoChih-Wen HuangYu-Ting ChenBang-Yu LiuChung-Ta LeePo-Lin ChenWen-Tsan ChangYun-Wen ChenTzer-Min LeeHui-Chen HsiehChang-Shi ChenNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Cheng-Rung Huang Cheng-Ju Kuo Chih-Wen Huang Yu-Ting Chen Bang-Yu Liu Chung-Ta Lee Po-Lin Chen Wen-Tsan Chang Yun-Wen Chen Tzer-Min Lee Hui-Chen Hsieh Chang-Shi Chen Host CDK-1 and formin mediate microvillar effacement induced by enterohemorrhagic Escherichia coli
description	Enterohemorrhagic Escherichia coli (EHEC) induces formation of attaching and effacing lesions in the intestine. Here, Huang et al. use human intestinal cells and a C. elegans model of infection to show that the process is mediated by a host signaling pathway involving cyclin-dependent kinase CDK1 and formin CYK1.
format	article
author	Cheng-Rung Huang Cheng-Ju Kuo Chih-Wen Huang Yu-Ting Chen Bang-Yu Liu Chung-Ta Lee Po-Lin Chen Wen-Tsan Chang Yun-Wen Chen Tzer-Min Lee Hui-Chen Hsieh Chang-Shi Chen
author_facet	Cheng-Rung Huang Cheng-Ju Kuo Chih-Wen Huang Yu-Ting Chen Bang-Yu Liu Chung-Ta Lee Po-Lin Chen Wen-Tsan Chang Yun-Wen Chen Tzer-Min Lee Hui-Chen Hsieh Chang-Shi Chen
author_sort	Cheng-Rung Huang
title	Host CDK-1 and formin mediate microvillar effacement induced by enterohemorrhagic Escherichia coli
title_short	Host CDK-1 and formin mediate microvillar effacement induced by enterohemorrhagic Escherichia coli
title_full	Host CDK-1 and formin mediate microvillar effacement induced by enterohemorrhagic Escherichia coli
title_fullStr	Host CDK-1 and formin mediate microvillar effacement induced by enterohemorrhagic Escherichia coli
title_full_unstemmed	Host CDK-1 and formin mediate microvillar effacement induced by enterohemorrhagic Escherichia coli
title_sort	host cdk-1 and formin mediate microvillar effacement induced by enterohemorrhagic escherichia coli
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/f4b63533b7a9482ab5bd4e6b416ad6a9
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Host CDK-1 and formin mediate microvillar effacement induced by enterohemorrhagic Escherichia coli

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