Control of transmembrane charge transfer in cytochrome c oxidase by the membrane potential

Cytochrome c oxidase (CytcO) is the last enzyme of the electron transport chain, but how the electrochemical membrane potential affects CytcO is unclear. Here the authors show that proton uptake to the catalytic site of CytcO and presumably proton translocation was impaired by the potential, but ele...

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Detalles Bibliográficos
Autores principales:	Markus L. Björck, Peter Brzezinski
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f4bcba95d2864bbaaa90dae138690215
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spelling	oai:doaj.org-article:f4bcba95d2864bbaaa90dae1386902152021-12-02T14:40:03ZControl of transmembrane charge transfer in cytochrome c oxidase by the membrane potential10.1038/s41467-018-05615-52041-1723https://doaj.org/article/f4bcba95d2864bbaaa90dae1386902152018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05615-5https://doaj.org/toc/2041-1723Cytochrome c oxidase (CytcO) is the last enzyme of the electron transport chain, but how the electrochemical membrane potential affects CytcO is unclear. Here the authors show that proton uptake to the catalytic site of CytcO and presumably proton translocation was impaired by the potential, but electron transfer was not affected.Markus L. BjörckPeter BrzezinskiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Markus L. Björck Peter Brzezinski Control of transmembrane charge transfer in cytochrome c oxidase by the membrane potential
description	Cytochrome c oxidase (CytcO) is the last enzyme of the electron transport chain, but how the electrochemical membrane potential affects CytcO is unclear. Here the authors show that proton uptake to the catalytic site of CytcO and presumably proton translocation was impaired by the potential, but electron transfer was not affected.
format	article
author	Markus L. Björck Peter Brzezinski
author_facet	Markus L. Björck Peter Brzezinski
author_sort	Markus L. Björck
title	Control of transmembrane charge transfer in cytochrome c oxidase by the membrane potential
title_short	Control of transmembrane charge transfer in cytochrome c oxidase by the membrane potential
title_full	Control of transmembrane charge transfer in cytochrome c oxidase by the membrane potential
title_fullStr	Control of transmembrane charge transfer in cytochrome c oxidase by the membrane potential
title_full_unstemmed	Control of transmembrane charge transfer in cytochrome c oxidase by the membrane potential
title_sort	control of transmembrane charge transfer in cytochrome c oxidase by the membrane potential
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/f4bcba95d2864bbaaa90dae138690215
work_keys_str_mv	AT markuslbjorck controloftransmembranechargetransferincytochromecoxidasebythemembranepotential AT peterbrzezinski controloftransmembranechargetransferincytochromecoxidasebythemembranepotential
_version_	1718390452673052672

Control of transmembrane charge transfer in cytochrome c oxidase by the membrane potential

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