Copy Number of an Integron-Encoded Antibiotic Resistance Locus Regulates a Virulence and Opacity Switch in <named-content content-type="genus-species">Acinetobacter baumannii</named-content> AB5075

Copy Number of an Integron-Encoded Antibiotic Resistance Locus Regulates a Virulence and Opacity Switch in <named-content content-type="genus-species">Acinetobacter baumannii</named-content> AB5075

ABSTRACT We describe a novel genetic mechanism in which tandem amplification of a plasmid-borne integron regulates virulence, opacity variation, and global gene expression by altering levels of a putative small RNA (sRNA) in Acinetobacter baumannii AB5075. Copy number of this amplified locus correla...

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Autores principales: Sarah E. Anderson, Chui Yoke Chin, David S. Weiss, Philip N. Rather
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
Acinetobacter
phenotypic switching
integron
sRNA
virulence regulation
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/f4bcc123c0db45ffb6f4a8e7f2b73b01
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