Copy Number of an Integron-Encoded Antibiotic Resistance Locus Regulates a Virulence and Opacity Switch in <named-content content-type="genus-species">Acinetobacter baumannii</named-content> AB5075

Copy Number of an Integron-Encoded Antibiotic Resistance Locus Regulates a Virulence and Opacity Switch in <named-content content-type="genus-species">Acinetobacter baumannii</named-content> AB5075

ABSTRACT We describe a novel genetic mechanism in which tandem amplification of a plasmid-borne integron regulates virulence, opacity variation, and global gene expression by altering levels of a putative small RNA (sRNA) in Acinetobacter baumannii AB5075. Copy number of this amplified locus correla...

Full description

Saved in:
Bibliographic Details
Main Authors: Sarah E. Anderson, Chui Yoke Chin, David S. Weiss, Philip N. Rather
Format: article
Language:EN
Published: American Society for Microbiology 2020
Subjects:
Acinetobacter
phenotypic switching
integron
sRNA
virulence regulation
Microbiology
QR1-502
Online Access:https://doaj.org/article/f4bcc123c0db45ffb6f4a8e7f2b73b01
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items