Evaluation of Rapid Diagnostic Tests for Assessment of Hepatitis B in Resource-Limited Settings

Chronic Hepatitis B (HBV) is the most important cause of liver disease worldwide. There is a need for low-cost tests to aid in diagnosis and management of HBV infection in resource-limited settings. We evaluated the utility of several rapid diagnostic tests (RDT) in three different continents (Europ...

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Autores principales: James S. Leathers, M. Belen Pisano, Viviana Re, Gertine van Oord, Amir Sultan, Andre Boonstra, Jose D. Debes
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Lenguaje:EN
Publicado: Ubiquity Press 2019
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Acceso en línea:https://doaj.org/article/f4bddf1efb624e89a687380b38276c23
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spelling oai:doaj.org-article:f4bddf1efb624e89a687380b38276c232021-12-02T06:49:29ZEvaluation of Rapid Diagnostic Tests for Assessment of Hepatitis B in Resource-Limited Settings2214-999610.5334/aogh.2562https://doaj.org/article/f4bddf1efb624e89a687380b38276c232019-07-01T00:00:00Zhttps://annalsofglobalhealth.org/articles/2562https://doaj.org/toc/2214-9996Chronic Hepatitis B (HBV) is the most important cause of liver disease worldwide. There is a need for low-cost tests to aid in diagnosis and management of HBV infection in resource-limited settings. We evaluated the utility of several rapid diagnostic tests (RDT) in three different continents (Europe, South America, Africa). The HBsAg RDT showed optimal sensitivity and specificity. The anti-HBeAb RDT showed acceptable sensitivity and excellent specificity. Our results suggest that these RDTs could be used for screening and management of HBV.James S. LeathersM. Belen PisanoViviana ReGertine van OordAmir SultanAndre BoonstraJose D. DebesUbiquity PressarticleInfectious and parasitic diseasesRC109-216Public aspects of medicineRA1-1270ENAnnals of Global Health, Vol 85, Iss 1 (2019)
institution DOAJ
collection DOAJ
language EN
topic Infectious and parasitic diseases
RC109-216
Public aspects of medicine
RA1-1270
spellingShingle Infectious and parasitic diseases
RC109-216
Public aspects of medicine
RA1-1270
James S. Leathers
M. Belen Pisano
Viviana Re
Gertine van Oord
Amir Sultan
Andre Boonstra
Jose D. Debes
Evaluation of Rapid Diagnostic Tests for Assessment of Hepatitis B in Resource-Limited Settings
description Chronic Hepatitis B (HBV) is the most important cause of liver disease worldwide. There is a need for low-cost tests to aid in diagnosis and management of HBV infection in resource-limited settings. We evaluated the utility of several rapid diagnostic tests (RDT) in three different continents (Europe, South America, Africa). The HBsAg RDT showed optimal sensitivity and specificity. The anti-HBeAb RDT showed acceptable sensitivity and excellent specificity. Our results suggest that these RDTs could be used for screening and management of HBV.
format article
author James S. Leathers
M. Belen Pisano
Viviana Re
Gertine van Oord
Amir Sultan
Andre Boonstra
Jose D. Debes
author_facet James S. Leathers
M. Belen Pisano
Viviana Re
Gertine van Oord
Amir Sultan
Andre Boonstra
Jose D. Debes
author_sort James S. Leathers
title Evaluation of Rapid Diagnostic Tests for Assessment of Hepatitis B in Resource-Limited Settings
title_short Evaluation of Rapid Diagnostic Tests for Assessment of Hepatitis B in Resource-Limited Settings
title_full Evaluation of Rapid Diagnostic Tests for Assessment of Hepatitis B in Resource-Limited Settings
title_fullStr Evaluation of Rapid Diagnostic Tests for Assessment of Hepatitis B in Resource-Limited Settings
title_full_unstemmed Evaluation of Rapid Diagnostic Tests for Assessment of Hepatitis B in Resource-Limited Settings
title_sort evaluation of rapid diagnostic tests for assessment of hepatitis b in resource-limited settings
publisher Ubiquity Press
publishDate 2019
url https://doaj.org/article/f4bddf1efb624e89a687380b38276c23
work_keys_str_mv AT jamessleathers evaluationofrapiddiagnostictestsforassessmentofhepatitisbinresourcelimitedsettings
AT mbelenpisano evaluationofrapiddiagnostictestsforassessmentofhepatitisbinresourcelimitedsettings
AT vivianare evaluationofrapiddiagnostictestsforassessmentofhepatitisbinresourcelimitedsettings
AT gertinevanoord evaluationofrapiddiagnostictestsforassessmentofhepatitisbinresourcelimitedsettings
AT amirsultan evaluationofrapiddiagnostictestsforassessmentofhepatitisbinresourcelimitedsettings
AT andreboonstra evaluationofrapiddiagnostictestsforassessmentofhepatitisbinresourcelimitedsettings
AT joseddebes evaluationofrapiddiagnostictestsforassessmentofhepatitisbinresourcelimitedsettings
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