Structures of Coxsackievirus A10 unveil the molecular mechanisms of receptor binding and viral uncoating

The disease-causing pathogen Coxsackievirus A10 (CVA10) is a human type-A Enterovirus. Here the authors present the cryo-EM structures of the mature CVA10 virion and the empty- and A-particles of CVA10, which is of interest for CVA10 vaccine development.

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Autores principales: Ling Zhu, Yao Sun, Jinyan Fan, Bin Zhu, Lei Cao, Qiang Gao, Yanjun Zhang, Hongrong Liu, Zihe Rao, Xiangxi Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/f4c447ec4f644093a5f2b9dd709a4b52
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spelling oai:doaj.org-article:f4c447ec4f644093a5f2b9dd709a4b522021-12-02T16:56:54ZStructures of Coxsackievirus A10 unveil the molecular mechanisms of receptor binding and viral uncoating10.1038/s41467-018-07531-02041-1723https://doaj.org/article/f4c447ec4f644093a5f2b9dd709a4b522018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07531-0https://doaj.org/toc/2041-1723The disease-causing pathogen Coxsackievirus A10 (CVA10) is a human type-A Enterovirus. Here the authors present the cryo-EM structures of the mature CVA10 virion and the empty- and A-particles of CVA10, which is of interest for CVA10 vaccine development.Ling ZhuYao SunJinyan FanBin ZhuLei CaoQiang GaoYanjun ZhangHongrong LiuZihe RaoXiangxi WangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ling Zhu
Yao Sun
Jinyan Fan
Bin Zhu
Lei Cao
Qiang Gao
Yanjun Zhang
Hongrong Liu
Zihe Rao
Xiangxi Wang
Structures of Coxsackievirus A10 unveil the molecular mechanisms of receptor binding and viral uncoating
description The disease-causing pathogen Coxsackievirus A10 (CVA10) is a human type-A Enterovirus. Here the authors present the cryo-EM structures of the mature CVA10 virion and the empty- and A-particles of CVA10, which is of interest for CVA10 vaccine development.
format article
author Ling Zhu
Yao Sun
Jinyan Fan
Bin Zhu
Lei Cao
Qiang Gao
Yanjun Zhang
Hongrong Liu
Zihe Rao
Xiangxi Wang
author_facet Ling Zhu
Yao Sun
Jinyan Fan
Bin Zhu
Lei Cao
Qiang Gao
Yanjun Zhang
Hongrong Liu
Zihe Rao
Xiangxi Wang
author_sort Ling Zhu
title Structures of Coxsackievirus A10 unveil the molecular mechanisms of receptor binding and viral uncoating
title_short Structures of Coxsackievirus A10 unveil the molecular mechanisms of receptor binding and viral uncoating
title_full Structures of Coxsackievirus A10 unveil the molecular mechanisms of receptor binding and viral uncoating
title_fullStr Structures of Coxsackievirus A10 unveil the molecular mechanisms of receptor binding and viral uncoating
title_full_unstemmed Structures of Coxsackievirus A10 unveil the molecular mechanisms of receptor binding and viral uncoating
title_sort structures of coxsackievirus a10 unveil the molecular mechanisms of receptor binding and viral uncoating
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/f4c447ec4f644093a5f2b9dd709a4b52
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