Gene editing and elimination of latent herpes simplex virus in vivo
Herpes simplex virus establishes lifelong latency in ganglionic neurons, which are the source for recurrent infection. Here Aubert et al. report a promising antiviral therapy based on gene editing with adeno-associated virus-delivered meganucleases, which leads to a significant reduction in ganglion...
Guardado en:
Autores principales: | Martine Aubert, Daniel E. Strongin, Pavitra Roychoudhury, Michelle A. Loprieno, Anoria K. Haick, Lindsay M. Klouser, Laurence Stensland, Meei-Li Huang, Negar Makhsous, Alexander Tait, Harshana S. De Silva Feelixge, Roman Galetto, Philippe Duchateau, Alexander L. Greninger, Daniel Stone, Keith R. Jerome |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/f4d037a80a34400ba2411e4046361719 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
In vivo dynamics of AAV-mediated gene delivery to sensory neurons of the trigeminal ganglia
por: Chung H. Dang, et al.
Publicado: (2017) -
Ultrasensitive Capture of Human Herpes Simplex Virus Genomes Directly from Clinical Samples Reveals Extraordinarily Limited Evolution in Cell Culture
por: Alexander L. Greninger, et al.
Publicado: (2018) -
A novel bioluminescent herpes simplex virus 1 for in vivo monitoring of herpes simplex encephalitis
por: Olus Uyar, et al.
Publicado: (2021) -
Dynamic Proteomics of Herpes Simplex Virus Infection
por: Nir Drayman, et al.
Publicado: (2017) -
Tracheitis Caused by Coinfection with Cytomegalovirus and Herpes Simplex Virus
por: Yu-Mi Lee, et al.
Publicado: (2021)