Single molecule multiplexed nanopore protein screening in human serum using aptamer modified DNA carriers

It is still a challenge for current nanopore sensing methods to differentiate multiple analytes from complex biological material. Here, the authors graft nucleic acid aptamer sequences along the backbone of a double stranded DNA carrier for the detection of multiple protein targets in human serum.

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Autores principales:	Jasmine Y. Y. Sze, Aleksandar P. Ivanov, Anthony E. G. Cass, Joshua B. Edel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f4d9252357194915982ab31463cf732e
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spelling	oai:doaj.org-article:f4d9252357194915982ab31463cf732e2021-12-02T14:40:25ZSingle molecule multiplexed nanopore protein screening in human serum using aptamer modified DNA carriers10.1038/s41467-017-01584-32041-1723https://doaj.org/article/f4d9252357194915982ab31463cf732e2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01584-3https://doaj.org/toc/2041-1723It is still a challenge for current nanopore sensing methods to differentiate multiple analytes from complex biological material. Here, the authors graft nucleic acid aptamer sequences along the backbone of a double stranded DNA carrier for the detection of multiple protein targets in human serum.Jasmine Y. Y. SzeAleksandar P. IvanovAnthony E. G. CassJoshua B. EdelNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jasmine Y. Y. Sze Aleksandar P. Ivanov Anthony E. G. Cass Joshua B. Edel Single molecule multiplexed nanopore protein screening in human serum using aptamer modified DNA carriers
description	It is still a challenge for current nanopore sensing methods to differentiate multiple analytes from complex biological material. Here, the authors graft nucleic acid aptamer sequences along the backbone of a double stranded DNA carrier for the detection of multiple protein targets in human serum.
format	article
author	Jasmine Y. Y. Sze Aleksandar P. Ivanov Anthony E. G. Cass Joshua B. Edel
author_facet	Jasmine Y. Y. Sze Aleksandar P. Ivanov Anthony E. G. Cass Joshua B. Edel
author_sort	Jasmine Y. Y. Sze
title	Single molecule multiplexed nanopore protein screening in human serum using aptamer modified DNA carriers
title_short	Single molecule multiplexed nanopore protein screening in human serum using aptamer modified DNA carriers
title_full	Single molecule multiplexed nanopore protein screening in human serum using aptamer modified DNA carriers
title_fullStr	Single molecule multiplexed nanopore protein screening in human serum using aptamer modified DNA carriers
title_full_unstemmed	Single molecule multiplexed nanopore protein screening in human serum using aptamer modified DNA carriers
title_sort	single molecule multiplexed nanopore protein screening in human serum using aptamer modified dna carriers
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/f4d9252357194915982ab31463cf732e
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Single molecule multiplexed nanopore protein screening in human serum using aptamer modified DNA carriers

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