Human tetherin exerts strong selection pressure on the HIV-1 group N Vpu protein.

HIV-1 groups M and N emerged within the last century following two independent cross-species transmissions of SIVcpz from chimpanzees to humans. In contrast to pandemic group M strains, HIV-1 group N viruses are exceedingly rare, with only about a dozen infections identified, all but one in individu...

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Main Authors: Daniel Sauter, Daniel Unterweger, Michael Vogl, Shariq M Usmani, Anke Heigele, Silvia F Kluge, Elisabeth Hermkes, Markus Moll, Edward Barker, Martine Peeters, Gerald H Learn, Frederic Bibollet-Ruche, Joëlle V Fritz, Oliver T Fackler, Beatrice H Hahn, Frank Kirchhoff
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
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Online Access:https://doaj.org/article/f4dc536a7092459b97d0a541b72626f2
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