Temporal regulation of Lsp1 O-GlcNAcylation and phosphorylation during apoptosis of activated B cells

B cell receptor (BCR) activation can trigger signalling causing apoptosis in order to eliminate auto-reactive B cells. Here the authors show that the O-GlcNAcylation and phosphorylation of lymphocyte-specific protein-1 are involved in a switch that regulates the initiation of apoptosis induced by BC...

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Autores principales:	Jung-Lin Wu, Hsin-Yi Wu, Dong-Yan Tsai, Ming-Feng Chiang, Yi-Ju Chen, Shijay Gao, Chun-Cheng Lin, Chun-Hung Lin, Kay-Hooi Khoo, Yu-Ju Chen, Kuo-I. Lin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f4ea53b30f1641559ce4aa1a196ad329
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spelling	oai:doaj.org-article:f4ea53b30f1641559ce4aa1a196ad3292021-12-02T14:39:53ZTemporal regulation of Lsp1 O-GlcNAcylation and phosphorylation during apoptosis of activated B cells10.1038/ncomms125262041-1723https://doaj.org/article/f4ea53b30f1641559ce4aa1a196ad3292016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12526https://doaj.org/toc/2041-1723B cell receptor (BCR) activation can trigger signalling causing apoptosis in order to eliminate auto-reactive B cells. Here the authors show that the O-GlcNAcylation and phosphorylation of lymphocyte-specific protein-1 are involved in a switch that regulates the initiation of apoptosis induced by BCR cross-linking.Jung-Lin WuHsin-Yi WuDong-Yan TsaiMing-Feng ChiangYi-Ju ChenShijay GaoChun-Cheng LinChun-Hung LinKay-Hooi KhooYu-Ju ChenKuo-I. LinNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jung-Lin Wu Hsin-Yi Wu Dong-Yan Tsai Ming-Feng Chiang Yi-Ju Chen Shijay Gao Chun-Cheng Lin Chun-Hung Lin Kay-Hooi Khoo Yu-Ju Chen Kuo-I. Lin Temporal regulation of Lsp1 O-GlcNAcylation and phosphorylation during apoptosis of activated B cells
description	B cell receptor (BCR) activation can trigger signalling causing apoptosis in order to eliminate auto-reactive B cells. Here the authors show that the O-GlcNAcylation and phosphorylation of lymphocyte-specific protein-1 are involved in a switch that regulates the initiation of apoptosis induced by BCR cross-linking.
format	article
author	Jung-Lin Wu Hsin-Yi Wu Dong-Yan Tsai Ming-Feng Chiang Yi-Ju Chen Shijay Gao Chun-Cheng Lin Chun-Hung Lin Kay-Hooi Khoo Yu-Ju Chen Kuo-I. Lin
author_facet	Jung-Lin Wu Hsin-Yi Wu Dong-Yan Tsai Ming-Feng Chiang Yi-Ju Chen Shijay Gao Chun-Cheng Lin Chun-Hung Lin Kay-Hooi Khoo Yu-Ju Chen Kuo-I. Lin
author_sort	Jung-Lin Wu
title	Temporal regulation of Lsp1 O-GlcNAcylation and phosphorylation during apoptosis of activated B cells
title_short	Temporal regulation of Lsp1 O-GlcNAcylation and phosphorylation during apoptosis of activated B cells
title_full	Temporal regulation of Lsp1 O-GlcNAcylation and phosphorylation during apoptosis of activated B cells
title_fullStr	Temporal regulation of Lsp1 O-GlcNAcylation and phosphorylation during apoptosis of activated B cells
title_full_unstemmed	Temporal regulation of Lsp1 O-GlcNAcylation and phosphorylation during apoptosis of activated B cells
title_sort	temporal regulation of lsp1 o-glcnacylation and phosphorylation during apoptosis of activated b cells
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/f4ea53b30f1641559ce4aa1a196ad329
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Temporal regulation of Lsp1 O-GlcNAcylation and phosphorylation during apoptosis of activated B cells

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