Subnanometre enzyme mechanics probed by single-molecule force spectroscopy
Adenylate kinase catalyses the interconversion of adenosine phosphates, and plays a crucial role in maintaining cellular energy homeostasis. Here, the authors use single molecule optical tweezers to understand how the enzyme’s conformation dynamics modulates catalysis.
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Autores principales: | Benjamin Pelz, Gabriel Žoldák, Fabian Zeller, Martin Zacharias, Matthias Rief |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/f4fe9840fe134709ad725d0e0b555534 |
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