Bio-surveillance of environmental pollutants in the population of Kinshasa, Democratic Republic of Congo (DRC): a small pilot study

Abstract Background Environmental pollutants are known to be ubiquitous and may present toxic effects (endocrine-disruption properties, carcinogenicity …) and represent a real threat to human health. The aim of the present pilot study was to assess the content of environmental pollutants (inorganic,...

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Autores principales:	Trésor Bayebila Menanzambi, Patrice Dufour, Catherine Pirard, Jean Nsangu, Jean-Pierre Mufusama, Jérémie Mbinze Kindenge, Roland Marini Djang’eing’a, Corinne Charlier
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Bio-surveillance Small pilot study Environmental pollutants Urine Serum Whole blood Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/f50976049fa548179dbbc30f3558290b
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spelling	oai:doaj.org-article:f50976049fa548179dbbc30f3558290b2021-11-21T12:12:06ZBio-surveillance of environmental pollutants in the population of Kinshasa, Democratic Republic of Congo (DRC): a small pilot study10.1186/s13690-021-00717-x2049-3258https://doaj.org/article/f50976049fa548179dbbc30f3558290b2021-11-01T00:00:00Zhttps://doi.org/10.1186/s13690-021-00717-xhttps://doaj.org/toc/2049-3258Abstract Background Environmental pollutants are known to be ubiquitous and may present toxic effects (endocrine-disruption properties, carcinogenicity …) and represent a real threat to human health. The aim of the present pilot study was to assess the content of environmental pollutants (inorganic, persistent, and non-persistent pollutants) in biological samples (urine, serum, and whole blood), collected from volunteers in Kinshasa, capital of Democratic Republic of Congo, in order to identify pollutants of interest and to design a protocol for a larger scale study. Methods From randomly selected 15 volunteers living in Kinshasa, aged from 25 to 66 years, (mean age = 43.4 years), including 10 men and 5 women, urine, whole blood, and serum samples were used in this study to estimate the contents in these environmental pollutants, using inductively coupled plasma mass spectrometry, gas chromatography coupled to mass spectrometry, and liquid chromatography coupled to mass spectrometry. Results When compared to data nationally and internationally available, the preliminary outcomes of this study indicated a very high level of exposure to environmental pollutants in the population of Kinshasa, especially for heavy metals, parabens and triclosan. To a lesser extent, contamination measured for glyphosate, phthalates, organochlorine pesticides, pyrethroids and dialkylphosphate pesticides was also significant. In contrast, the investigated population of Kinshasa was found to be weakly exposed to other persistent organic pollutants like polychlorinated biphenyls, brominated flame retardants, phenolic organohalogens, and perfluoroalkyl substances. Conclusion Although the biologic fluids were collected from a limited number of volunteers (n = 15), the results of the present report clearly indicate that the population of Kinshasa is not spared by the investigated environmental pollutants. Moreover, this study gives us important information to design a larger scale study protocol.Trésor Bayebila MenanzambiPatrice DufourCatherine PirardJean NsanguJean-Pierre MufusamaJérémie Mbinze KindengeRoland Marini Djang’eing’aCorinne CharlierBMCarticleBio-surveillanceSmall pilot studyEnvironmental pollutantsUrineSerumWhole bloodPublic aspects of medicineRA1-1270ENArchives of Public Health, Vol 79, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Bio-surveillance Small pilot study Environmental pollutants Urine Serum Whole blood Public aspects of medicine RA1-1270
spellingShingle	Bio-surveillance Small pilot study Environmental pollutants Urine Serum Whole blood Public aspects of medicine RA1-1270 Trésor Bayebila Menanzambi Patrice Dufour Catherine Pirard Jean Nsangu Jean-Pierre Mufusama Jérémie Mbinze Kindenge Roland Marini Djang’eing’a Corinne Charlier Bio-surveillance of environmental pollutants in the population of Kinshasa, Democratic Republic of Congo (DRC): a small pilot study
description	Abstract Background Environmental pollutants are known to be ubiquitous and may present toxic effects (endocrine-disruption properties, carcinogenicity …) and represent a real threat to human health. The aim of the present pilot study was to assess the content of environmental pollutants (inorganic, persistent, and non-persistent pollutants) in biological samples (urine, serum, and whole blood), collected from volunteers in Kinshasa, capital of Democratic Republic of Congo, in order to identify pollutants of interest and to design a protocol for a larger scale study. Methods From randomly selected 15 volunteers living in Kinshasa, aged from 25 to 66 years, (mean age = 43.4 years), including 10 men and 5 women, urine, whole blood, and serum samples were used in this study to estimate the contents in these environmental pollutants, using inductively coupled plasma mass spectrometry, gas chromatography coupled to mass spectrometry, and liquid chromatography coupled to mass spectrometry. Results When compared to data nationally and internationally available, the preliminary outcomes of this study indicated a very high level of exposure to environmental pollutants in the population of Kinshasa, especially for heavy metals, parabens and triclosan. To a lesser extent, contamination measured for glyphosate, phthalates, organochlorine pesticides, pyrethroids and dialkylphosphate pesticides was also significant. In contrast, the investigated population of Kinshasa was found to be weakly exposed to other persistent organic pollutants like polychlorinated biphenyls, brominated flame retardants, phenolic organohalogens, and perfluoroalkyl substances. Conclusion Although the biologic fluids were collected from a limited number of volunteers (n = 15), the results of the present report clearly indicate that the population of Kinshasa is not spared by the investigated environmental pollutants. Moreover, this study gives us important information to design a larger scale study protocol.
format	article
author	Trésor Bayebila Menanzambi Patrice Dufour Catherine Pirard Jean Nsangu Jean-Pierre Mufusama Jérémie Mbinze Kindenge Roland Marini Djang’eing’a Corinne Charlier
author_facet	Trésor Bayebila Menanzambi Patrice Dufour Catherine Pirard Jean Nsangu Jean-Pierre Mufusama Jérémie Mbinze Kindenge Roland Marini Djang’eing’a Corinne Charlier
author_sort	Trésor Bayebila Menanzambi
title	Bio-surveillance of environmental pollutants in the population of Kinshasa, Democratic Republic of Congo (DRC): a small pilot study
title_short	Bio-surveillance of environmental pollutants in the population of Kinshasa, Democratic Republic of Congo (DRC): a small pilot study
title_full	Bio-surveillance of environmental pollutants in the population of Kinshasa, Democratic Republic of Congo (DRC): a small pilot study
title_fullStr	Bio-surveillance of environmental pollutants in the population of Kinshasa, Democratic Republic of Congo (DRC): a small pilot study
title_full_unstemmed	Bio-surveillance of environmental pollutants in the population of Kinshasa, Democratic Republic of Congo (DRC): a small pilot study
title_sort	bio-surveillance of environmental pollutants in the population of kinshasa, democratic republic of congo (drc): a small pilot study
publisher	BMC
publishDate	2021
url	https://doaj.org/article/f50976049fa548179dbbc30f3558290b
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Bio-surveillance of environmental pollutants in the population of Kinshasa, Democratic Republic of Congo (DRC): a small pilot study

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