Role of Ser102 and Ser104 as regulators of cGMP hydrolysis by PDE5A.
<h4>Background</h4>Phosphodiesterases (PDEs) cleave phosphodiester bonds in cyclic nucleotides and play diverse roles in cell biology. PDE5A is a cytoplasmic phosphodiesterase which specifically degrades cyclic guanosine monophosphate (cGMP), a cell signaling molecule that plays importan...
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Main Authors: | Julie Carøe Nordgaard, Lars Schack Kruse, Steen Gammeltoft, Christina Rostrup Kruuse |
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Format: | article |
Language: | EN |
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Public Library of Science (PLoS)
2014
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Online Access: | https://doaj.org/article/f50aa976ce4248b6b5e99ad2e06f2210 |
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