Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development

Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development

Uterine gland development is essential for successful embryo implantation, decidua formation and placental development. Here the authors demonstrate that neonatal Wnt-dependent Lgr5 expressing stem/progenitor cells at the tips of developing glands are indispensable for uterine gland development.

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Autores principales: Ryo Seishima, Carly Leung, Swathi Yada, Katzrin Bte Ahmed Murad, Liang Thing Tan, Amin Hajamohideen, Si Hui Tan, Hideki Itoh, Kazuhiro Murakami, Yoshihiro Ishida, Satoshi Nakamizo, Yusuke Yoshikawa, Esther Wong, Nick Barker
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Q
Acceso en línea:https://doaj.org/article/f5147bce6d4b4b9782f63d84b4e894c4
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spelling oai:doaj.org-article:f5147bce6d4b4b9782f63d84b4e894c42021-12-02T16:57:07ZNeonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development10.1038/s41467-019-13363-32041-1723https://doaj.org/article/f5147bce6d4b4b9782f63d84b4e894c42019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13363-3https://doaj.org/toc/2041-1723Uterine gland development is essential for successful embryo implantation, decidua formation and placental development. Here the authors demonstrate that neonatal Wnt-dependent Lgr5 expressing stem/progenitor cells at the tips of developing glands are indispensable for uterine gland development.Ryo SeishimaCarly LeungSwathi YadaKatzrin Bte Ahmed MuradLiang Thing TanAmin HajamohideenSi Hui TanHideki ItohKazuhiro MurakamiYoshihiro IshidaSatoshi NakamizoYusuke YoshikawaEsther WongNick BarkerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ryo Seishima
Carly Leung
Swathi Yada
Katzrin Bte Ahmed Murad
Liang Thing Tan
Amin Hajamohideen
Si Hui Tan
Hideki Itoh
Kazuhiro Murakami
Yoshihiro Ishida
Satoshi Nakamizo
Yusuke Yoshikawa
Esther Wong
Nick Barker
Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development
description Uterine gland development is essential for successful embryo implantation, decidua formation and placental development. Here the authors demonstrate that neonatal Wnt-dependent Lgr5 expressing stem/progenitor cells at the tips of developing glands are indispensable for uterine gland development.
format article
author Ryo Seishima
Carly Leung
Swathi Yada
Katzrin Bte Ahmed Murad
Liang Thing Tan
Amin Hajamohideen
Si Hui Tan
Hideki Itoh
Kazuhiro Murakami
Yoshihiro Ishida
Satoshi Nakamizo
Yusuke Yoshikawa
Esther Wong
Nick Barker
author_facet Ryo Seishima
Carly Leung
Swathi Yada
Katzrin Bte Ahmed Murad
Liang Thing Tan
Amin Hajamohideen
Si Hui Tan
Hideki Itoh
Kazuhiro Murakami
Yoshihiro Ishida
Satoshi Nakamizo
Yusuke Yoshikawa
Esther Wong
Nick Barker
author_sort Ryo Seishima
title Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development
title_short Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development
title_full Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development
title_fullStr Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development
title_full_unstemmed Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development
title_sort neonatal wnt-dependent lgr5 positive stem cells are essential for uterine gland development
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/f5147bce6d4b4b9782f63d84b4e894c4
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