Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development

Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development

Uterine gland development is essential for successful embryo implantation, decidua formation and placental development. Here the authors demonstrate that neonatal Wnt-dependent Lgr5 expressing stem/progenitor cells at the tips of developing glands are indispensable for uterine gland development.

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Bibliographic Details
Main Authors: Ryo Seishima, Carly Leung, Swathi Yada, Katzrin Bte Ahmed Murad, Liang Thing Tan, Amin Hajamohideen, Si Hui Tan, Hideki Itoh, Kazuhiro Murakami, Yoshihiro Ishida, Satoshi Nakamizo, Yusuke Yoshikawa, Esther Wong, Nick Barker
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Science
Q
Online Access:https://doaj.org/article/f5147bce6d4b4b9782f63d84b4e894c4
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